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PCOS IN ADOLESCENT GIRLS AND YOUNG WOMEN: TOWARD A TREATMENT GUIDED BY PATHOPHYSIOLOGY (SPIOMET4HEALTH) KU Leuven

Francis de Zegher
Woman and Child

Polycystic Ovary Syndrome (PCOS) is the most prevalent, chronic endocrine-metabolic disorder of adolescents and young women (AYAs), affecting 5-10% of AYAs worldwide. It is the most frequent cause of anovulatory subfertility. There is no approved therapy for PCOS. Standard off-label treatment with oral contraceptives reverts neither the underlying pathophysiology nor the associated co-morbidities
Pilot studies have generated new insights ...

Unlocking preventive oral care for adults with severe mental illness: identifying oral health determinants as a basis for developing oral health promoting interventions. KU Leuven

Joke Duyck
LUCAS - Centre for Care Research and Consultancy, Population Studies in Oral Health
Oral health of people with severe mental illness (SMI) is significantly worse than that of the general population and often deteriorates rapidly as mental health issues develop. The resulting pain, discomfort, tooth loss etc. place an additional mental burden, affecting self-esteem and self-stigma, and making recovery and societal reintegration more challenging. As the majority of oral health problems, e.g. caries and periodontitis, are largely ...

Consortium Preventive Oral Health Care as partner organisation for preventive oral health care in a risk population. KU Leuven

Joke Duyck
Population Studies in Oral Health

This project aims to contribute to facilitate oral health and prevention of oral disease of the population, and more specifically in risk populations by means of development of methodologies, sensitisation, structural measures, as well as help and guidance during implementation of the latter by intermediate organisations. The populations will be reached by relevant intermediate organisations in order to achieve the policy priorities and ...

Optimalisation of the interRAI Suite of Instruments as a tool for assessing and facilitating oral health and evaluation of its relation to general health of frail older persons. KU Leuven

Joke Duyck
Population Studies in Oral Health, TRANSFORM, Leuven Biostatistics and Statistical Bioinformatics Centre (L-BioStat), Academic Center for General Practice
The generally poor oral health in frail elderly can be optimised by using the interRAI Suite of Instruments (interRAI-SoI), designed to assess an older persons need for care. The instrument consists of a questionnaire on important health as-pects. Algorithms translate the data into alerts that trigger assessment protocols, which in turn lead to individual care paths. The interRAI-SoI also includes non-vali-dated basic oral health related ...

Health Innovation Living Lab - Oral Health (EXT) UCLL

Peter Vos, Doris Voortmans
UC Leuven, Health Innovation Leu

Praktijkgericht onderzoek binnen het domein van mondgezondheid draagt bij tot innovatie, het verbeteren van de gezondheidszorg- en preventie en het commercialiseerbaar maken van een gezonde mond. In dit samenspel is het voortdurend zoeken naar evenwicht tussen de praktijk èn fundamenteel onderzoek. Een gezonde mond is een belangrijke voorwaarde om fysiek én mentaal mee te kunnen in onze maatschappij. Daarom is mondzorg geen luxe: iedereen ...

Exploring microbiological modulation possibilities for oral health KU Leuven

Wim Teughels
Periodontology & Oral Microbiology
Periodontitis is a frequently encountered infectious disease that affects about 80% of the adults. Approximately 10 to 15% of these adults suffer from a severe form, in which the accompanied inflammatory process will result in the destruction of the supporting tissues of the teeth. Whenleft untreated, periodontitis can lead to loosening and subsequent lossof teeth. Periodontitis is considered to be a polymicrobial infection. The mouth is very ...

Study of the oral health status of the Belgian population Ghent University

Martijn Lambert
Department of Oral Health Sciences, Sciensano (Belgium), Université Catholique de Louvain, KU Leuven, Université Libre de Bruxelles

Commissioned by the National Institute for Health and Disability Insurance (NIHDI), an oral health survey in Belgium is being organised for the third time (Oral Health Data Registration and Evaluation System – OHDRES). This oral health survey is being conducted following the National Health Survey 2023 in collaboration with Sciensano and the Interuniversity Cell Epidemiology (ICE), a consortium of researchers affiliated with KU Leuven, ...

Evolution of oral health in Belgium Ghent University

Martijn Lambert
Department of Oral Health Sciences
Background Within Mondgezondheid en Maatschappij (Dental Public Health), research is conducted into health inequalities within the population, and possible interventions to improve oral health, with special attention to individuals with social or other vulnerabilities. In 2023–2024, a descriptive study on oral health was carried out on a representative sample of the Belgian population (n=7001), commissioned by the NIHDI (RIZIV). Data were ...

Oral bacteria and health Ghent University

Marie Joossens
Department of Biochemistry and microbiology

The most diverse and most densely populated habitats in human are the gut and the oral cavity. While these environments are anatomically distinct and each provide a different environment to microorganisms, their interplay has significant implications for human health and disease. The oral cavity, as the primary gateway to the gastrointestinal tract, facilitates microbial transfer to the gut, shaping downstream microbial communities. However, ...