Projects
Cell-wall degrading enzyme inhibition and health beneficial effects of phenolic compounds by solid-state fermentation from brassica waste Ghent University
This project will investigate the bioactivities of phenolic
compounds from brassica waste after solid-state fermentation. It aims to search the
binding mechanisms of flavonoids to the cell-wall degrading enzymes by structureactivity
relationship (QSAR) study and investigate their anti-obesity and antihypertension
activities in vivo and in vitro.
Phenolic compounds as anti-hypertensive, anti-obesity and anti-microbial agents Ghent University
Production of Brassica leads to a hugh amount of by-products, rich in phenolic compounds. In this study, extracts rich in phenolic compounds will be prepared, after treating the by-products using enzymes and/or micro-organisms. These extracts will be characterized based on the phenolic compounds present by UPLC-MS. Also the extracts will be tested on their bio-activity potential, i.e. ACE-inhibitory, CCK1-receptor and anti-microbial activity, ...