Projects
Field versus observer perspective in mental imagery: an investigation of the effects on mood and behaviour, and of the efficacy of a clinical application in the prevention of depressive relapse. KU Leuven
mso-ansi-language:EN-US" lang="EN-US">It isnot just a posit</>ive event in itself, but also how it is processed that
determines the outcome, for instance on positive affect. This is especially of
interest in the context of depression. Depression is characterised by increased
negative affect, but also by reduced positiveaffect</>. Our aim
was to investigate mechanisms that ...
Freedom of expression endangered in the digital age? A critical legal analysis of the regulation of online hate speech in Europe Hasselt University
Freedom of expression endangered in the digital age? A critical legal analysis of the regulation of online hate speech in Europe Hasselt University
PrevenD 2.0: Implementation of gamified cognitive control training to prevent recurrence of depression Ghent University
The goal of PrevenD 2.0 is to deliver a freely accessible, cost-effective,
preventive intervention for (recurrent) depression and guide
implementation in clinical practice. For this purpose, we aim to
maximize the impact of a recently developed and proven effective
preventive gamified cognitive control training (CCT) procedure for
remitted depressed patients (developed and tested in PrevenD 1.0). In ...
Non-Amyloid Pathological Brain Aging in Late Life Depression KU Leuven
Depression and age-related brain disorders such as dementia are together one of the greatest public health issues of our time. With a rapidly increasing aging population and longer life expectancy, the burden associated with depression in later life will only increase. Understanding the neurobiological mechanisms underlying depression is crucial for limiting the personal and economic impact of the disorder by improving diagnosis and ...
Multimodal PET-MRI brain imaging of white matter pathology in late life depression KU Leuven
Depression in later life (late-life depression: LLD) is a common but debilitating psychiatric disorder, which is associated with cerebrovascular disease. Understanding the neurobiological mechanisms underlying LLD is crucial for new solutions for its prevention and treatments. Previous studies have revealed that macrostructural white matter damage is associated with LLD, but little is known about microstructural alterations. The aim of this ...
Dopaminergic modulation of memory generalisation in depression. KU Leuven
The neural system that establish integrated episodic memory (i.e., memory about “what happened where and when”) comprises different forebrain and midbrain areas, including the neurochemically and functionally distinct VTA system that originates in the brainstem and provides the major dopaminergic input (i.e., releasing the neurotransmitter dopamine) to the forebrain. This proposal focusses on memory generalization (i.e., the ability to ...
When does interpretation bias go awry? A cognitive-interpersonal investigation of the nature, correlates, and consequences of interpretation inflexibility in depression. Ghent University
Improving our understanding of mechanisms underlying depression is vital to advance current
treatments. Cognitive-interpersonal theories postulate that a bias toward inferring negative
interpretations of social information plays a crucial role in vulnerability to depression. Yet, it
remains unclear how this interpretation bias exerts its toxic effects. In three research lines, this
project expands on the novel ...
Unraveling the link between depression and dementia Vrije Universiteit Brussel
The amount of patients and care providers confronted with these
illnesses is expected to rise significantly due to aging populations, posing a significant individual and societal burden. Current research suggests depression may be a risk factor for the development of dementia in some people, as well as that it may be the first symptom of dementia in others, while ...