Researcher
Mathieu Bertrand
- Keywords (Ghent University):regulated cell death, cytokines, inflammation
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Molecular and cell biology not elsewhere classified, Posttranslational modifications, Cell death and senescence, Inflammation, Innate immunity, Cell signalling
Affiliations
- Vandenabeele Lab (Research group)
Member
From1 Jan 2017 → Today - Department of Biomedical molecular biology (Department)
Member
From1 Mar 2009 → Today
Projects
1 - 10 of 14
- Endosomal Micro-Autophagy as a New Cell Death Checkpoint in the TNF PathwayFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Novel mechanisms of inflammation and cell death regulation in autoinflammatory and infectious diseasesFrom1 Jan 2023 → TodayFunding: BOF - projects
- Cell Death Regulation and Role in Infection and Inflammatory DiseasesFrom1 Jan 2022 → TodayFunding: FWO EOS
- Autophagy in inflammation and inflammatory disorders (ATLANTIS), from basic insights to experimental therapyFrom1 Jan 2021 → TodayFunding: BOF - iBOF
- Identification of RIPK1 substrates and elucidation of their action mechanism in inflammationFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Study of RIPK1 involvement and regulation in inflammatory and infectious diseasesFrom1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- The study of RIPK1 phosphorylation in TNF-mediated infection and diseaseFrom1 Oct 2017 → 30 Sep 2020Funding: FWO fellowships
- Unraveling the role of RIPK1 phosphorylation in TNF-mediated cell
death and inflammationFrom1 Jan 2017 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
- Pre-allocated professorship in cell deathFrom1 Feb 2016 → 31 Jan 2021Funding: BOF - ZAP BOF mandates
- Characterization of MAGED1 as a negative regulator of NOD1/2 immunityFrom1 Jan 2016 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 79
- Cell death checkpoints in the TNF pathway(2023)
Authors: Jon Huyghe, Dario Priem, Mathieu Bertrand
Pages: 628 - 643 - Inhibition of RIPK1 kinase does not affect diabetes development : beta-cells survive RIPK1 activation(2023)
Authors: Tatiana Takiishi, Peng Xiao, Marie Franchimont, Eduardo H. Gilglioni, Erick N. Arroba, Esteban N. Gurzov, Mathieu Bertrand, Alessandra K. Cardozo
- NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis(2023)
Authors: Yves Dondelinger, Dario Priem, Jon Huyghe, Tom Delanghe, Peter Vandenabeele, Mathieu Bertrand
- From PERK to RIPK1 : design, synthesis and evaluation of novel potent and selective necroptosis inhibitors(2023)
Authors: Camilla Scarpellini, Sophie Valembois, Kenneth Goossens, Mike Vadi, Caroline Lanthier, Greta Klejborowska, Pieter Van der Veken, Hans De Winter, Mathieu Bertrand, Koen Augustyns
- LC3-independent autophagy is vital to prevent TNF cytotoxicity(2023)
Authors: Dario Priem, Jon Huyghe, Mathieu Bertrand
Pages: 2585 - 2589 - Death by TNF : a road to inflammation(2023)
Authors: Geert van Loo, Mathieu Bertrand
Pages: 289 - 303 - Apoptotic cell death in disease : current understanding of the NCCD 2023(2023)
Authors: Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart A Aaronson, John M Abrams, Dieter Adam, Massimiliano Agostini, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, et al.
Pages: 1097 - 1154 - Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2023)
Authors: Jelle Verhoeven, Kathryn A. Jacobs, Francesca Rizzollo, Francesca Lodi, Yichao Hua, Joanna Poźniak, Adhithya Narayanan Srinivasan, Diede Houbaert, Gautam Shankar, Sanket More, et al.
- RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD(2023)
Authors: Hannelore Van Eeckhoutte, Chantal Donovan, Richard Y. Kim, Thomas M. Conlon, Meshal Ansari, Haroon Khan, Ranjith Jayaraman, Nicole G. Hansbro, Yves Dondelinger, Tom Delanghe, et al.
- Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells(2022)
Authors: Sam Blanchett, Yves Dondelinger, Alessandro Barbarulo, Mathieu Bertrand, Benedict Seddon