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Researcher
Johan Neyts
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Faculty of Medicine (Faculty)
Member
From1 Oct 2000 → 30 Sep 2002 - Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Infrastructure
1 - 1 of 1
Projects
71 - 80 of 82
- Use of optimized pluripotent stem cell derived hepatocytes for evaluation of the biology of viral replication of hepatitis viruses.From1 Sep 2012 → 31 Dec 2016Funding: IWT personal funding - strategic basic research grants
- Antiviral strategies against polio and other enterovirusesFrom1 Oct 2011 → 12 Jan 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- Towards the development of potent and selective inhibitors of hepatitis E virus.From1 Oct 2011 → 30 Sep 2015Funding: FWO fellowships
- Interactomics analysis of the replication of Flaviviridae: in search of novel druggable targetsFrom26 Sep 2011 → 1 Sep 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Evaluation of the preprotein translocation motor SecA as a target for the development of novel antibioticsFrom8 Oct 2010 → 27 Aug 2015Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of potent and broad-spectrum inhibitors of rhinoviruses for the treatment/prophylaxis of rhinovirus infections of patients with asthma and COPD.From13 Sep 2010 → 29 Jan 2015Funding: IWT personal funding - strategic basic research grants
- Mechanistic study on virus entry and replication. A fundamental approach to the development of new and specific antiviral chemotherapeutics.From1 Jan 2010 → 31 Dec 2014Funding: BOF - Concerted Research Project from 1994
- Antiviral strategies for the global eradication of polioFrom31 Aug 2009 → 31 Dec 2009Funding: Other international institutions, not mentioned elsewhere
- Novel strategies to selectively inhibit hepatitis C virus replication and to prevent the development of drug resistant variants.From1 Jan 2009 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Biodiversity and emerging viruses in the Indian Ocean: selection of natural drug candidates to fight the Chikungunya virus.From14 Nov 2008 → 13 Nov 2010Funding: Other European institutions (outside EU)
Publications
1 - 10 of 621
- Mechanism of action of phthalazinone derivatives against rabies virus.(2024)
Authors: Dirk Jochmans, Johan Neyts
Pages: 105838 - Design, synthesis, and molecular modeling studies of novel 2-quinolone-1,2,3-triazole-α-aminophosphonates hybrids as dual antiviral and antibacterial agents.(2024)
Authors: Johan Neyts, Dirk Jochmans, Steven De Jonghe
Pages: 116235 - Beware of drug resistance: Let's not lose tecovirimat against mpox.(2024)
Authors: Johan Neyts, Laurens Liesenborghs
Pages: 276 - 278 - Molnupiravir inhibits human norovirus and rotavirus replication in 3D human intestinal enteroids.(2024)
Authors: Jana Van Dycke, Johan Neyts, Jelle Matthijnssens, Joana Duarte Da Rocha Pereira
Pages: 105839 - Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study.(2024)
Authors: Simon Feys, Sam Vanmassenhove, Bram Boeckx, Seppe Cambier, Yves Debaveye, Greet Hermans, Katrien Lagrou, Johan Neyts, Marijke Peetermans, Joana Duarte Da Rocha Pereira, et al.
Pages: e247 - e260 - Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor(2024)
Authors: Suzanne Kaptein, Johan Neyts
Pages: 4063 - 4082 - Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted(2024)
Authors: Dirk Jochmans, Rana Abdelnabi, Birgit Weynand, Johan Neyts
- Studies of the human-to-human spread of respiratory pathogens.(2024)
Authors: Emmanuel Andre, Johan Neyts
- Genetic consequences of effective and suboptimal dosing with mutagenic drugs in a hamster model of SARS-CoV-2 infection(2024)
Authors: Rana Abdelnabi, Johan Neyts
- Design, synthesis, and lead optimization of piperazinyl-pyrimidine analogues as potent small molecules targeting the viral capping machinery of Chikungunya virus(2024)
Authors: Rana Abdelnabi, Johan Neyts, Leen Delang
Patents
1 - 10 of 10
- Corona virus binders (Inventor)
- Lassavirus vaccines (Inventor)
- Chimeric filovirus vaccines (Inventor)
- Chimeric zika-japanese encephalitis virus (Inventor)
- Chimeric yellow fever zika virus strain (Inventor)
- Viral replication inhibitors (Inventor)
- Treatment and prevention of dengue disease (Inventor)
- Coronavirus vaccines (Inventor)
- Design synthesis and methods of use of acyclic fleximer nucleoside analogues having anti-coronavirus activity (Inventor)
- Treatment and prevention of dengue disease (Inventor)