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Researcher
John Creemers
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Biochemical Neuroendocrinology (Division)
Responsible
From1 Jan 2006 → Today - Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
11 - 20 of 26
- The role of the proprotein convertase Furin in diabetes and obesity.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project
- The role of the proprotein convertase furin in cancerFrom22 Sep 2014 → 3 Aug 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Clinical and molecular characterization of a novel congenital disease; the role of PREPL in regulated secretion and neuromuscular transmissionFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project
- The role of PREPL in regulated secretion and neuromuscular transmission.From21 Aug 2011 → 14 Sep 2014Funding: FWO fellowships
- Evaluation of the role of the proprotein convertase furin in liver: involvement in non-alcoholic steatohepatitis and hepatocellular carcinoma.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project
- Characterization of the regulated secretory pathway in neurons of a mouse model for autism.From1 Oct 2010 → 21 Mar 2016Funding: Private funding of national origin - undefined, FWO fellowships
- Functional characterization of non-synonymous variants in PC1/3 that confer risk of obesity in Europeanen.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
- The role of furine in the liver: characterization of a new mouse model of NASH.From9 Nov 2009 → 6 Nov 2015Funding: IWT personal funding - strategic basic research grants
- Functional Peptidomics Knowledge Platform.From1 Oct 2009 → 30 Sep 2013Funding: IOF - Industrial Research Fund
- FURINHIB: validation of furin as a therapeutic target in cancers with poor prognosis using novel inhibitor.From1 Sep 2009 → 31 Dec 2010Funding: BOF - VIS/COF
Publications
1 - 10 of 91
- Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation.(2023)
Authors: John Creemers
Pages: 106 - 118 - Epigenetic modulations of immune cells: from normal development to tumor progression(2023)
Authors: John Creemers
Pages: 5120 - 5144 - Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice(2022)
Authors: Ilaria Coppola, Ceyhun Alar, John Creemers
- The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance(2022)
Authors: John Creemers
- Hypergastrinemia, a clue leading to the identification of an atypical form of diabetes mellitus type 2(2022)
Authors: John Creemers
Pages: 79 - 83 - Role of Furin in Colon Cancer Stem Cells Malignant Phenotype and Expression of LGR5 and NANOG in KRAS and BRAF-Mutated Colon Tumors(2022)
Authors: John Creemers
- The proprotein convertase furin in cancer: more than an oncogene(2022)
Authors: John Creemers
Pages: 1252 - 1262 - Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function(2021)
Authors: John Creemers
- Het ontrafelen van de rol van PREPL, een serine hydrolase gedeleteerd in een Prader-Willi-achtig syndroom(2021)
Authors: Karen Rosier, John Creemers
- In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23(2021)
Authors: John Creemers