Researcher
Kevin Braeckmans
- Keywords:nanomedicines, biophotonics, medical nanotechnology, drug delivery, microscopy
- Disciplines:Nanobiotechnology, Nanoscale characterisation, Nanophotonics, Nanometrology, In vitro testing, Biopharmaceuticals, Non-clinical studies, Nanomaterials, Medical nanotechnology, Biopharmaceutics, Physical pharmacy
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Aug 1999 → Today
Infrastructure
1 - 4 of 4
- Flanders BioImaging (Consortium partner)
- A multimodal non-linear optical platform for 2l3-photon excitation and 2ndl3rd harmonic imaging deep inside living tissues and animals (Consortium partner)
- Confocal and two-photon Microscope (Consortium coordinator)
- Stimulated Emission Depletion Microscope (Consortium coordinator)
Projects
11 - 20 of 56
- White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imagingFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Ultrafast-scanning tandem ICP-mass spectrometer for interference-free and highly-sensitive transient signal monitoringFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Light for life: high contrast multimodal medical imaging using inorganic fluorophoresFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Perturbation of apolipoprotein E4 (apoE4) activity in AD pathology using single domain antibodies and targeting them to the brainFrom1 Nov 2021 → TodayFunding: BOF - doctoral mandates
- Photo-induced destruction of protein aggregates and liquefaction of the vitreous humour using light sensitive nanomaterials.From1 Nov 2021 → 31 Aug 2022Funding: FWO senior postdoctoral fellowship
- Exploring the market potential of photoporation as the next generation of intracellular delivery technology for the R&D and cell therapy marketsFrom1 Feb 2021 → 31 Jul 2022Funding: H2020 - Frontier Research (ERC)
- FB-III (“FB triple-I”) : Flanders BioImaging: Integrating Imaging Infrastructure from cell to man.From1 Feb 2021 → 31 Jan 2023Funding: FWO International research infrastructure (IRI)
- Extracellular vesicle (EV) transport across the brain barriers: from mechanistic and biological insights towards strategies for delivery of therapeutics to the brain.From1 Jan 2021 → TodayFunding: BOF - projects
- Light-triggered self-assembled nanostructures for efficient and safe production of engineered therapeutic immune cellsFrom1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Combining photoporation with electrophoresis for improved transfection of hard-to-transfect cellsFrom1 Oct 2020 → TodayFunding: BOF - projects
Publications
1 - 10 of 235
- Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics(2024)
Authors: Jana Ramon, Yanou Engelen, Herlinde De Keersmaecker, Ilia Goemaere, Deep Punj, Julián Mejía Morales, Cédric Bonte, Geert Berx, Esther Hoste, Stephan Stremersch, et al.
Pages: 1019 - 1036 - Nucleic acid degradation as barrier to gene delivery : a guide to understand and overcome nuclease activity(2024)
Authors: Heyang Zhang, Jo Vandesompele, Kevin Braeckmans, Stefaan De Smedt, Katrien Remaut
Pages: 317 - 360 - Novel opto-fluidic drug delivery system for efficient cellular transfection(2023)
Authors: Majid Layachi, Anthony Treizebré, Laurent Hay, David Gilbert, Jean Pesez, Quentin D’Acremont, Kevin Braeckmans, Quentin Thommen, Emmanuel Courtade
- Designing of gradient scaffolds and their applications in tissue regeneration(2023)
Authors: Ananya Pattnaik, A. Swaroop Sanket, Sanghamitra Pradhan, Rajashree Sahoo, Sudiptee Das, Swarnaprbha Pany, Timothy E. L. Douglas, Rambabu Dandela, Qiang Liu, Jaykumar Rajadas, et al.
- Photothermal nanomaterial-mediated photoporation(2023)
Authors: Ranhua Xiong, Félix Sauvage, Juan Fraire, Chaobo Huang, Kevin Braeckmans
Pages: 631 - 643 - Capric acid and myristic acid permeability enhancers in curved liposome membranes(2023)
Authors: Samaneh Davoudi, Koen Raemdonck, Kevin Braeckmans, An Ghysels
Pages: 6789 - 6806 - Laser‐scanning microscopy for electrophoretic mobility characterization of single nanoparticles(2023)
Authors: Lucas Oorlynck, Yera Ussembayev, Ingrid Amer Cid, Juan Fraire, Charlotte Hinnekens, Kevin Braeckmans, Filip Strubbe
- Delivery of macromolecules in unstimulated T cells by photoporation with polydopamine nanoparticles(2023)
Authors: Dominika Berdecka, Aranit Harizaj, Ilia Goemaere, Deep Punj, Glenn Goetgeluk, Stijn De Munter, Herlinde De Keersmaecker, Veerle Boterberg, Winnok H. De Vos, Kevin Braeckmans
Pages: 680 - 693 - Laser-scanning imaging and electrophoresis of single nanoparticles(2022)Volume: 12131
Authors: Filip Strubbe, Lucas Oorlynck, Yera Ussembayev, Juan Fraire, Charlotte Hinnekens, Kevin Braeckmans, David Andrews, Angus Bain, Jean-Michel Nunzi
Number of pages: 1 - The cellular response to plasma membrane disruption for nanomaterial delivery(2022)
Authors: Gaëlle Houthaeve, Kevin Braeckmans, Winnok H. De Vos
Patents
1 - 9 of 9
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method to increase the permeability of the plasma membrane of cells and a structure suitable for use in such method (Inventor)
- Method and device to provide a microfluidic flow (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Method and system for dispersion measurements (Inventor)