Researcher
Max Mazzone
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Morphological sciences, Oncology
- See also: Mazzone Max (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Mazzone Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → 30 Sep 2022
Projects
41 - 50 of 62
- CRYPTIC TRANSCRIPTS: THE MASKED HEROES WHO BREAK TUMOR IMMUNE TOLERANCE AND FREE THE RESPONSE TO IMMUNE THERAPY.From1 Oct 2015 → 31 Jul 2021Funding: FWO fellowships
- Podoplanin-Expressing Macrophages (PoEMs) Promote Lymphangiogenesis and Lymphoinvasion in Breast CancerFrom18 Aug 2015 → 6 Nov 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Exploring the metabolic pathways driving tumor-associated macrophage polarization and their influence on tumor progression.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Podoplanin: the missing link between breast cancer and lymphatic metastasis?From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Mir-210 at the crossroad of M2 and M1 macrophage polarization: relevance for sepsis and cancer.From1 Jan 2015 → 31 Dec 2017Funding: FWO research grant KAN
- Exploring the metabolic pathways driving tumorassociated macrophage polarization and their influence on tumor progression..From1 Oct 2014 → 30 Sep 2018Funding: FWO fellowships
- The neurovascular link: an unexpectedly important role of metabolism.From1 Oct 2014 → 30 Sep 2021Funding: BOF - Methusalem
- GLUD1 inhibition promotes macrophage-mediated glutamine release, enhancing satellite cell activation and muscle regenerationFrom2 Sep 2014 → 20 Jun 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Identification of candidate biomarkers of intrinsic and acquired resistance to anti-angiogenic agents in metastatic colorectal cancer.From1 Jan 2013 → 31 Dec 2014Funding: Private funding of national origin - undefined
- Unraveling the role of Neuropilin 1 in tumor-associated macrophages : implications for therapy.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 179
- A Metabolic Gene Survey Pinpoints Fucosylation as a Key Pathway Underlying the Suppressive Function of Regulatory T Cells in Cancer(2023)
Authors: Ria Pinioti, Susan Schlenner, Bernard Thienpont, Abhishek Garg, Max Mazzone
Pages: 1611 - 1629 - Candida albicans stimulates formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection(2023)
Authors: Max Mazzone
- A metabolic gene survey pinpoints fucosylation as a key pathway underlying the suppressive function of Regulatory T cells in cancer.(2023)
Authors: Ria Pinioti, Max Mazzone, Mario di Matteo
Number of pages: 19 - Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding(2023)
Authors: Maxim De Schepper, Tatjana Geukens, Stefaan Soenen, Christine Desmedt, Colinda Scheele, Anna Sablina, Max Mazzone
- A collaborative synthetase(2023)
Authors: Max Mazzone
Pages: 255 - 256 - PHD2 Constrains Antitumor CD8+T-cell Activity(2023)
Authors: Max Mazzone
Pages: 339 - 350 - A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling(2023)
Authors: Ginevra Doglioni, Alex Cuadros, Xiaozheng Liu, dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Margherita Demicco, François Richard, Tatjana Geukens, Maxim De Schepper, et al.
Pages: 344 - + - Mitochondria metabolism sets the species-specific tempo of neuronal development(2023)
Authors: Ryohei Iwata, Pierre Casimir, Emir Erkol, Sofie Beckers, Anke Vandekeere, Pieter Vermeersch, Sebastien Carpentier, Kristofer Davie, Max Mazzone, Stein Aerts, et al.
Pages: 553 - + - Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer(2023)
Authors: Federica Cappellesso, Max Mazzone, Baki Topal
Number of pages: 37 - Stroma-derived miR-214 coordinates tumor dissemination.(2023)
Authors: Max Mazzone
Pages: 20
Patents
1 - 10 of 10
- Cd8+ t-cells lacking plexins and their application in cancer treatment (Inventor)
- Cancer treatment by targeting plexins in the immune compartment (Inventor)
- Biomarker for anti-tumor therapy (Inventor)
- Combination of p2y6 inhibitors and immune checkpoint inhibitors (Inventor)
- Inhibition of slc4a4 in the treatment of cancer (Inventor)
- Means and methods to treat inflammatory diseases (Inventor)
- Glutamine dehydrogenase inhibitors for use in muscle regeneration (Inventor)
- Cd8+ t-cells lacking plexins and their application in cancer treatment (Inventor)
- Podoplanin positive macrophages (Inventor)
- Cancer treatment by targeting plexins in the immune compartment (Inventor)