< Back to previous page
Researcher
Sandra Liekens
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Department of Microbiology, Immunology and Transplantation (Department)
Member
From1 Dec 2019 → Today - Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → 31 Dec 2019
Projects
1 - 7 of 7
- Structure-based discovery of positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor as cognition enhancers.From1 Oct 2016 → 30 Sep 2018Funding: IOF - Industrial Research Fund
- Vascular-disrupting agents (VDA): mechanism of action and anti-tumor activityFrom1 Feb 2016 → 6 Jan 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- An automated platform for multiparameter data collection on live pathogens of higher or unknown biosafety risk.From26 Jun 2014 → 31 Dec 2018Funding: Hercules - Large scale research infrastructure
- Role of receptor tyrosine kinases and associated gangliosides in influenza virus replicationFrom1 Oct 2012 → 21 Dec 2020Funding: BOF - Doctoral projects
- Mechanistic study on virus entry and replication. A fundamental approach to the development of new and specific antiviral chemotherapeutics.From1 Jan 2010 → 31 Dec 2014Funding: BOF - Concerted Research Project from 1994
- Dengue virus infection of endothelial cells: Pathogenesis and antiviral potential of glycosaminoglycan targetingFrom1 Sep 2009 → 29 Sep 2015Funding: Own budget, for example: patrimony, inscription fees, gifts
- The effect of Mycoplasma enzymes on the antiviral and anticancer activity of nucleoside analoguesFrom1 Jun 2008 → 2 Dec 2013Funding: IWT personal funding - strategic basic research grants
Publications
41 - 50 of 113
- Structure-activity relationship studies on a Trp dendrimer with dual activities against HIV and enterovirus A71. Modifications on the amino acid(2017)
Authors: Liang Sun, Jan Balzarini, Sam Noppen, Sandra Liekens, Dominique Schols, Johan Neyts, Pieter Leyssen, Carmen Mirabelli
Pages: 32 - 40 - Antivascular and antitumor properties of the tubulin-binding chalcone TUB091(2017)
Authors: Sam Noppen, Mohammed Benkheil, Sandra Liekens
Pages: 14325 - 14342 - High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300(2016)
Authors: Mariya Petrova, Sam Noppen, Sandra Liekens, Jan Balzarini, Dominique Schols, Jos Vanderleyden, Sarah Lebeer
Pages: 37339 - Bioluminescent avian pathogenic Escherichia coli for monitoring colibacillosis in experimentally infected chickens(2016)
Authors: Sam Noppen, Sandra Liekens, Rob Lavigne, Bruno Goddeeris
Pages: 87 - 92 - Blocking blood flow to solid tumors by destabilizing tubulin: An approach to targeting tumor growth(2016)
Authors: Sandra Liekens
Pages: 8685 - 8711 - Carbohydrate-binding non-peptidic pradimicins for the treatment of acute sleeping sickness in murine models(2016)
Authors: Sandra Liekens, Jan Balzarini
- Metal-free route for the synthesis of 4-acyl-1,2,3-triazoles from readily available building blocks(2016)
Authors: Vince Goyvaerts, Sandra Liekens, Wim Dehaen
Pages: 9966 - 9970 - A single-step acid catalyzed reaction for rapid assembly of NH-1,2,3-triazoles(2016)
Authors: Sampad Jana, Sandra Liekens, Wim Dehaen
Pages: 9236 - 9239 - Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones(2016)
Authors: Sandra Liekens, Jan Balzarini
Pages: 579 - Screening platform toward new anti-HIV aptamers set on molecular docking and fluorescence quenching techniques(2016)
Authors: Sam Noppen, Sandra Liekens, Jan Balzarini
Pages: 2327 - 34
Patents
1 - 2 of 2
- Novel anti-cancer thiophene compounds (Inventor)
- Anti-cancer compounds (Inventor)