Researcher
Sarah-Maria Fendt
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Biochemistry and metabolism, Medical systems biology, Molecular and cell biology, Oncology
- See also: Fendt SM (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Cellular Metabolism and Metabolic Regulation (VIB-KU Leuven) (Division)
Responsible
From1 Oct 2013 → Today - Fendt Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory of Cellular Metabolism and Metabolic Regulation (VIB-KU Leuven) (Division)
Member
From1 Jan 2013 → Today
Projects
1 - 10 of 40
- The Role of Metabolism in Metastasis FormationFrom27 Feb 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting cell surface receptors to inhibit metastatic growthFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting Mfrn2 to inhibit breast cancer-derived metastasis formation in lung and liver.From1 Oct 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting the dependence of liver metastases on the hypoxia-induced expression of nutrient transporters.From1 Oct 2023 → 2 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of Spatial metabolomics methods by DESI and MALDI for cancer researchFrom25 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Lipid metabolism in obesity and aging-induced cancer metastasisFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting the heterotypic cell communication networks at the perivascular niche to detect andintercept the early metastatic processFrom1 Jan 2023 → TodayFunding: BOF - iBOF
- Inhibiting iron metabolism to target metastasesFrom1 Oct 2022 → TodayFunding: BOF - projects
- Predicting metastasis formation based on cancer cells with a distinct energy metabolismFrom1 Oct 2022 → TodayFunding: BOF - projects
- Desorption electrospray ionization multi reflecting TOF: DESI XS SELECT SERIES MRTFrom2 Aug 2022 → TodayFunding: Other federal scientific institutions
Publications
11 - 20 of 128
- In vivo CRISPR Screen of SLC Transporters Defines Microenvironment-specific Metabolic Dependencies of Metastasis(2023)
Authors: Alex Cuadros, Sarah-Maria Fendt
- Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy(2023)
Authors: Ali Talebi, Vincent de Laat, Xander Spotbeen, Jonas Dehairs, Ginevra Doglioni, David Nittner, Tania Roskams, Patrizia Agostinis, Oliver Bechter, Veerle Boecxstaens, et al.
- Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia(2023)
Authors: Mitsugu Shimobayashi, Anke Vandekeere, Sarah-Maria Fendt
- Serum methylmalonic acid concentrations at breast cancer diagnosis are not associated with distant metastases(2023)
Authors: Sigrid Hatse, Anke Vandekeere, Yentl Lambrechts, François Richard, Annouschka Laenen, Patrick Neven, Ines Nevelsteen, Beppe Floris, Christine Desmedt, Sarah-Maria Fendt, et al.
- Palmitate oxidation drives a pro-metastatic post-translational modification(2023)
Authors: Sarah-Maria Fendt
Pages: 315 - 316 - CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions(2023)
Authors: Sarah-Maria Fendt
Pages: 452 - + - A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling(2023)
Authors: Ginevra Doglioni, Alex Cuadros, Xiaozheng Liu, dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Margherita Demicco, François Richard, Tatjana Geukens, Maxim De Schepper, et al.
Pages: 344 - + - Mitochondria metabolism sets the species-specific tempo of neuronal development(2023)
Authors: Ryohei Iwata, Pierre Casimir, Emir Erkol, Sofie Beckers, Anke Vandekeere, Pieter Vermeersch, Sebastien Carpentier, Kristofer Davie, Max Mazzone, Stein Aerts, et al.
Pages: 553 - + - Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution(2023)
Authors: Sarah-Maria Fendt
- Investigating the role of fatty acid desaturation in cancer(2022)
Authors: Sarah-Maria Fendt