Projects

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Uniqueness of human tooth morphology in medical imaging for human dental identification purpose KU Leuven

Patrick Thevissen
Department of Imaging & Pathology, Orthodontics, Oral and Maxillo-facial Surgery - Imaging & Pathology (OMFS-IMPATH)

Human dental identification (HDI) is based on the comparison of post-mortem (PM) and ante-mortem (AM) collected odontological evidences. The quality and quantity of these evidences play an essential role in providing a positive identification. In open identification cases positive dentalidentification is established under the assumption that the human dentition is unique for each individual.

In forensic identification practice an ...

Imaging the link between metabotropic and ionotropic signaling in vivo KU Leuven

Matthias Schönberger
Radiopharmaceutical Research
Cellular communication is a prerequisite for the life of multicellular organisms. Evolution has given rise to a variety of messenger systems that differ in speed and range. The communication between the outside and the inside of a cell is a key interface that is largely orchestrated by transmembrane receptors. This family of communication proteins can be roughly divided into two classes: 1) Metabotropic receptors, which trigger intracellular ...

Strategic Research Programme: Molecular Imaging and targeting of macrophages in Inflammation (ITARMI) Vrije Universiteit Brussel

Tony Lahoutte
Cellular and Molecular Immunology, Department of Bio-engineering Sciences, Medical Imaging, Translational Imaging Research Alliance, Supporting clinical sciences
Investigates specific biological questions in intact living subjects using non-invasive imaging based on emission tomography and optical imaging in combination with anatomical imaging (CT and MRI) and Targeting of inflammation linked to infectious diseases and cancer

In vivo imaging and therapy using labeled antibody derivatives KU Leuven

Guy Bormans
Radiopharmaceutical Research

Glycans play a central role in numerous events in cell-cell recognition, cell communication and cell mobility. Errors in glycan architecture and expression level can lead to pathologies such as cancer. Tumor Associated Carbohydrate Antigens (TACA) are specific glycans that can serve as biomarkers for tumor diagnostics as is already the case for carcinoembryogenic antigen (CEA). This project will focus on the xeno-glycan Neu5Gc ...

Special merit regarding social valorisation - call 2012 Vrije Universiteit Brussel

Wim Distelmans
Medical Imaging and Physical Sciences, Translational Radiation Oncology and Physics
Technology transfer (sometimes called "'valorisation") involves the transfer of (intellectual) property rights on academic knowledge through sale, or permission for its development, to a recipient third party, e.g. government institutions and businesses. Thus the recipient obtains the right to develop the acquired knowledge further into a product (in the broadest possible sense of the word) which may then be developed commercially, either by the ...

Translational Molecular Imaging Program for the University of Antwerp: application driven preclinical research. University of Antwerp

Steven Staelens
Molecular Imaging, Pathology, Radiotherapy & Oncology (MIPRO)
Given the demographic aging, research in molecular imaging has a large social support and bearing. Moreover, the successful miniaturization of (S)PE(C)T cameras these past three to five years caused a major breakthrough for small animal imaging. Dedicated high-resolution small animal imaging systems have recently emerged as important new tools for research and have entered the preclinical arena. These new imaging systems permit researchers to ...

Local models and local convergence for maximum likelihood iterative reconstruction KU Leuven

Johan Nuyts
Nuclear Medicine & Molecular Imaging, ESAT - PSI, Processing Speech and Images






Iterative methods are being increasingly used for
reconstruction of tomographic data as in computed tomography (CT) and positron
emission tomography (PET). These methods often yield better reconstructions
compared to analytical methods. An important reason for this is that iterative
reconstruction has a more flexible data acquisition model which allows for a
more accurate ...

Image Reconstruction and Analysis for Positron Emission Tomography in Oncology KU Leuven

Frederik Maes
Production Engineering, Machine Design and Automation (PMA) Section, ESAT - PSI, Processing Speech and Images
PET/CT is an important imaging tool in the diagnosis and treatment follow-up in oncology. Currently, the PET and CT images are reconstructed independently. In this project, the anatomical information provided by theCT image will be used during PET reconstruction to improve quantitativeaccuracy. For the definition of target volumes in radiotherapy and for treatment follow-up, the lesions should be delineated as accurate as possible. Often, ...