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Online efficiency maximization of drivetrains using a calorimeter in the loop (CALORIL) Ghent University

Jeroen De Kooning
Department of Electromechanical, Systems and Metal Engineering

Drivetrains are increasingly becoming more efficient, integrated and modular. This challenges the state of the art techniques in both loss measurement and modelling. The key innovation of CALORIL is to harness the superior loss measurement accuracy of a calorimeter by online iteration in a loop to resolve the following industrial needs in a time-effective manner: (1) efficient loss model calibration, including coupled subcomponents in ...

Development of a Next Calorimeter for Future Particle Physics Experiments Ghent University

Dirk Ryckbosch
Department of Physics and astronomy

Particle Physics experiments at future accelerators, like the International Linear Collider, will require a new generation of calorimeters with high 3D-granularity which enables the use of particle flow techniques. Within the CALICE R&D Collaboration we work on prototypes of a hadronic calorimeter with a semi-digital readout system and Glass Resistive Plate Chambers or Micro-Pattern Gas Detector as active detection medium.

Micro-Isothermal Titration Calorimeter: The Missing Link in Molecular Interaction Analysis for Supramolecular Chemistry Research Ghent University

José Martins
Department of Organic and Macromolecular Chemistry

This proposal requests funding for a micro-Isothermal Titration Calorimeter (micro-ITC), a sensitive, label-free technique that quantifies heat changes during intermolecular interactions. Micro-ITC provides direct access to key thermodynamic parameters (ΔH, ΔS, ΔG, KA) and interaction stoichiometry, offering deep insight into reversible interactions in supramolecular systems governed by weak forces. Despite its relevance to the applicants’ ...

Exploratory research into the employability of indirect calorimetry in function of nutritional advice in oncology patients in active treatment. VIVES

Lien Devriendt
Food
The great heterogeneity of the intensive care unit population (ICU) has led to a growing need for knowledge about the individual energy needs of each patient. In case of illness or trauma, the metabolism changes, making it necessary to adjust the diet. Hospitals use indirect calorimeters to map residual energy expenditure (REE). The output of this measurement forms the basis of nutritional therapy and is considered the gold standard in the ICU. ...

Fast scanning chip calorimetry combined with time resolved X-ray diffraction: a new view on polymer crystallization and melting KU Leuven

Bart Goderis
Polymer Chemistry and Materials

In the last decades, different fast scanning calorimetry (FSC) techniques have been developed, able to operate at scanning rates up to 40000 °C/s and higher. To allow for such rates, sub microgram samples are required. Relating calorimetric events to structural changes in minute amounts of material is a major challenge in high speed calorimetry. To be able to characterize materials under FSC conditions, we developed a unique setup, combining ...

Investigation of liquid crystalline compounds and their mixtures with mesogens, non-mesogens and nanoparticles by high-resolution adiabatic scanning calorimetry KU Leuven

Christ Glorieux
Soft Matter and Biophysics
Calorimetric techniques and in particular slow scanning adiabatic techniques have contributed substantially to our present understanding of phase transition in many soft matter systems.  There are however many kinds of phase transition several soft matter systems that are not or poorly understood.  In this project we use adiabatic scanning calorimetry to arrive at high-resolution data for phase transitions in the following ...

Calorimetry and upscaling of organic opto-electronic materials. University of Antwerp

Frank Blockhuys
Structural chemistry group (STRUCCHEM)
The proposed project studies the upscaling of three reactions for the synthesis of PPV oligomers with proven opto-electronic properties. The goal of the project is to determine, from a process point of view, the most suitable product and synthesis method from three possible candidates. In addition, a method will be optimized to determine heats of reaction based on quantum chemical calculations, and from the calorimetric experiments fundamental ...

Differential scanning calorimetry (DSC) to study interactions in complex food systems Ghent University

Koen Dewettinck
Department of Food Technology, Safety and Health, Department of Green Chemistry and Technology

Food products are structured composites of lipids, proteins and carbohydrates. Understanding the complex interactions between these components and their behavior during processing, storage and consumption, is a prerequisite to design more nutritious, sustainable and tasty foods. To achieve this, differential scanning calorimetry (DSC) is an indispensable tool allowing the study of phase or state transitions involved in food ingredients and ...

Optimization of the synthesis of diarylphosphonate inhibitors of serin proteases using reaction calorimetry. University of Antwerp

Koen Augustyns
Medicinal Chemistry (UAMC)
The synthesis of diaryl phosphonates, inhibitors of serine proteases, will be optimized and scaled up using reaction calorimetry. The reaction variables that allow for a more efficient Birum-Oleksyszyn reaction, will be identified and studied. In addition, general applicability of results will be assessed during the preparation of a library of potential serine protease inhibitors using a broader spectrum of synthetic substrates.