Projects
Profiling (sub)clonal architecture and phylogeny in tumors by novel techniques for whole-genome sequence data mining and single-cell genome sequencing. KU Leuven
Affymetrix microarray genomics-transcriptomics platform. Vrije Universiteit Brussel
Deciphering hidden inheritance patterns using advanced data mining techniques on high throughput genomic data. University of Antwerp
Selection of driver genes and neuronal differentiation gene modules in neuroblastoma through an integrated genomic analysis Ghent University
Integrative genomic analyses and pathway reconstruction efforts will be implemented to the currently used set of analytical tools as an original and powerful approach to discriminate driver from passenger mutations in the next-generation sequencing of neuroblastoma tumor samples. Gene modules will be obtained and those implicated in normal sympathetic neuronal differentiation will be prioritized for further functional analyses.
Deciphering the molecular pathogenesis of neuroblastoma through next generation genome analysis Ghent University
In this project, the newest technologies in human genetics (massively parallel sequencing and ultra-high throughput qPCR) will be used to better understand the molecular mechanisms causing neuroblastoma, a highly lethal pediatric malignancy, with perspectives for development of targeted therapies.
A genomic approach for the identification of genes involved in mental retardation and brain anomalies. KU Leuven
The role of BRCA1 in maintaining genomic integrity Ghent University
Belgian Genome Biobank Ghent University
International efforts in human genomics have led to major
break-throughs in our understanding of the genetic basis of
rare and common diseases. Variation between populations
in disease prevalence and distribution of genetic variants
necessitates access to population-based genetic reference
datasets. Human genomics is making a transition ...
Belgian Genome Biobank KU Leuven
International efforts in human genomics have led to major
break-throughs in our understanding of the genetic basis of
rare and common diseases. Variation between populations
in disease prevalence and distribution of genetic variants
necessitates access to population-based genetic reference
datasets. Human genomics is making a transition from
being largely research to health-care driven in Europe as
many ...