Projects
Characterization of biophysical stromal properties in human cancer: towards personalized computational oncology Ghent University
In recent years, there has been increasing interest in the application of methods and techniques
from applied sciences in cancer research. An important domain in which this
expertise can be particularly useful, is the study of the transport mechanisms of chemotherapy
through the tissue in the treatment of cancer with chemotherapy. It is indeed known,
that the abnormal structure and properties of the tumor tissue (the ...
Quality in Molecular Oncology Testing Laboratories in Europe: a View from Different Angles KU Leuven
Increased knowledge about the molecular mechanisms involved in cancer pathogenesis has led to the development of novel targeted therapies for various cancer types. In order to have an effective treatment, knowledge about the mutation status of certain genes is often required. The European Medicines Agency (EMA) and the U.S. Food and Drug Administration (FDA) decided, for example, that wild-type RAS status is required prior to ...
Interaction of quorum sensing peptides with human cells: applications in oncology and immunology Ghent University
IWT / SB-2014 batch IWT / SB / Verbeke Frederick / 131356 Intercatie of quorum sensing peptides with human cells: applications in oncology and immunology
Conversations of terminal status: development of a guidance tool for a clinical intervention trial in oncology Vrije Universiteit Brussel
However, not informing the patient of terminal status often results in futile treatment, overly burdening the patient and making unnecessary costs and use of ...
Image Reconstruction and Analysis for Positron Emission Tomography in Oncology KU Leuven
COLUMBO: Engineered CRISPR toolbox for revolutionizing single-cell genome imaging in embryogenesis and oncology KU Leuven
Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction) KU Leuven
Validation of Actionable Genomic ABerrations in a paediatric Oncology Network for Doctorate students Ghent University
Pre-clinical drug development for paediatric cancers is very complex, resource intensive and requiring multi-disciplinary expertise and innovative approaches. The VAGABOND ITN, consisting of 12 academic and 6 non-academic partners from 8 European countries, aims to create a multidisciplinary and multi-sectoral program to validate new therapeutic interventions in paediatric cancer. This network will be sustainable embedded in the ITCC ...
Exploring the use of extracellular RNA in liquid biopsies for precision oncology purposes Ghent University
The discovery that cancer cells actively and passively release their content into the blood stream has opened enormous opportunities for characterizing cancer cells without the need for surgery to access tumor tissue Instead, a simple drop of blood is sufficient to detect and characterize cancer cells inside a patient’ body The use of circulating DNA molecules has spurred this field, but the study of circulating RNA molecules also seems ...