Blood plasma and FFPE derived total RNA seq dataset from DLBCL and PMBCL patients

The goal of this study was to investigate cell-free RNA (cfRNA) biomarkers in DLBCL and PMBCL patients. Blood plasma samples (n=168) and matched diagnostic formalin-fixed paraffin-embedded (FFPE) tissue samples (n=69) of DLBCL patients, PMBCL patients and healthy controls were collected between 2016-2021. Plasma samples were collected at diagnosis, at interim evaluation, after treatment, and in case of refractory or relapsed disease. RNA was extracted from 200 µl plasma using the miRNeasy serum/plasma kit and from FFPE tissue using the miRNeasy FFPE kit. RNA was subsequently sequenced on a NovaSeq 6000 instrument using the SMARTer Stranded Total RNA-seq pico v3 library preparation kit.

Jaar van publicatie:2023

Toegankelijkheid:restricted

Original language:EN

Uitgever:European Genome-Phenome Archive

Licentie:CC-BY-NC-ND-4.0

Formaat:fastqgz

Trefwoorden: Dataset