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Onderzoeker
Lujia Zhou
- Disciplines:Neurowetenschappen, Biologische en fysiologische psychologie, Cognitieve wetenschappen en intelligente systemen, Ontwikkelingspsychologie en veroudering
Affiliaties
- Laboratorium voor Onderzoek naar Neurodegeneratieve Ziektes (VIB-KU Leuven) (Labo)
Lid
Vanaf15 apr 2009 → 31 mrt 2011
Projecten
1 - 1 of 1
- Antilichaam gebaseerde inhibitie en functionele studie van BACE1, het Beta-secretase in de ziekte van AlzheimerVanaf1 dec 2008 → 27 okt 2011Financiering: Eigen Middelen zoals patrimonium, inschrijvingsgelden, giften, ....
Publicaties
1 - 10 van 11
- Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau(2018)Gepubliceerd in: NeuronISSN: 0896-6273Issue: 4Volume: 97Pagina's: 823 - 835
- Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse(2015)Gepubliceerd in: Cell ReportsISSN: 2211-1247Issue: 9Volume: 12Pagina's: 1367 - 76
- Fast and efficient Drosophila melanogaster gene knock-ins using MiMIC transposons.(2014)Gepubliceerd in: G3-Genes Genomes GeneticsISSN: 2160-1836Issue: 12Volume: 4Pagina's: 2381 - 2387
- Ultrafast Synaptic Endocytosis Cycles to the Center Stage(2014)Gepubliceerd in: Developmental CellISSN: 1534-5807Issue: 1Volume: 28Pagina's: 5 - 6
- BACE1 Levels Correlate With Phospho-Tau Levels In Human Cerebrospinal Fluid(2013)Gepubliceerd in: Current Alzheimer ResearchISSN: 1567-2050Issue: 7Volume: 10Pagina's: 671 - 8
- The mechanism of gamma-Secretase dysfunction in familial Alzheimer disease(2012)Gepubliceerd in: EMBO JournalISSN: 0261-4189Issue: 10Volume: 31Pagina's: 2261 - 2274
- The Neural Cell Adhesion Molecules L1 and CHL1 Are Cleaved by BACE1 Protease in Vivo(2012)Gepubliceerd in: Journal of Biological ChemistryISSN: 0021-9258Issue: 31Volume: 287Pagina's: 25927 - 25940
- The Neural Cell Adhesion Molecules L1 and CHL1 Are Cleaved by BACE1 Protease in Vivo(2012)Gepubliceerd in: Journal of Biological ChemistryISSN: 0021-9258Issue: 31Volume: 287Pagina's: 25927 - 25940
- ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1(2011)Gepubliceerd in: Proceedings of the National Academy of Sciences of the United States of AmericaISSN: 0027-8424Issue: 34Volume: 108Pagina's: E559 - E568
- Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β'-site increases Aβ generation(2011)Gepubliceerd in: EMBO Molecular MedicineISSN: 1757-4676Issue: 5Volume: 3Pagina's: 291 - 302
Patenten
1 - 9 van 9
- Screening method for synaptogyrin-3 inhibitors
- Targeting synaptogyrin-3 in tauopathy treatment
- Targeting synaptogyrin-3 in tauopathy treatment
- Targeting synaptogyrin-3 in tauopathy treatment
- Single domain antibodies capable of modulating bace activity
- Single domain antibodies capable of modulating bace activity
- Inhibition of tau-mediated early synaptic dysfunction
- Bace1 inhibitory antibodies
- BACE1 inhibitory antibodies