Synthetic and Structural Exploration of [2(4)]Tetrathiacalix[2]arene[2]pyrimidines

Korte inhoud:A novel class of two atom bridged metacyclophanes-[2(4)]thiacalix[2]arene[2]pyrimidines-has been synthesized via a straightforward S(N)Ar reaction. The conformational properties and intra-annular dimensions of the [2(4)]thiacalix[2]arene[2]pyrimidines were evaluated by X-ray structure analysis and compared with known homothia- and thiacalixarenes. Post-macrocyclization oxidation of the bridging sulfur moieties resulted in a [2(4)]sulfonylcalix[2]arene[2]pyrimidine, which gave access to an unexplored cavity size among sulfonylcalixarenes.

Jaar van publicatie:2012

Trefwoorden:Organische en medische scheikunde

BOF-keylabel:ja

IOF-keylabel:ja

BOF-publication weight:3

CSS-citation score:1

Authors from:Higher Education

Toegankelijkheid:Open

Reviewstatus:Peer-reviewed