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Oligonucleotide promoted peptide bond formation using a tRNA mimicking approach

Tijdschriftbijdrage - Tijdschriftartikel

TransferRNA's role in protein translation is the prime example of an Informational Leaving Group (ILG). A simplified model produced oligophenylalanine with a modified uracil as an ILG in the presence of specific oligonucleotides. Our preliminary studies contribute to the importance of hybrid species in bridging the gap between peptides and nucleic acids.
Tijdschrift: Chemical Communications
ISSN: 1359-7345
Issue: 36
Volume: 53
Pagina's: 5013 - 5016
Jaar van publicatie:2017
BOF-keylabel:ja
IOF-keylabel:ja
BOF-publication weight:2
CSS-citation score:1
Authors from:Higher Education
Toegankelijkheid:Closed