LC Assay for a HIV Tablet Containing Emtricitabine, Tenofovir Disoproxil Fumarate and Rilpivirine

Korte inhoud:A liquid chromatographic method with UV detection was developed for the assay of a tablet for HIV (human immunodeficiency virus) treatment containing three active components, which are emtricitabine, tenofovir disoproxil fumarate and rilpivirine. A Hypersil BDS-C18 column was used as stationary phase and the assay was performed with gradient elution using mobile phases containing acetonitrile, 0.2 M potassium dihydrogen phosphate and water. Dimethyl sulfoxide-distilled water (1:1) was used as solvent for the active components. The method proved to be selective, linear, repeatable, sensitive and easy to perform.

Jaar van publicatie:2011

Trefwoorden:Analytische, anorganische en nucleaire scheikunde, Biochemie & -fysica en Moleculaire biologie

BOF-keylabel:ja

IOF-keylabel:ja

BOF-publication weight:1

CSS-citation score:1

Authors from:Private, Higher Education

Toegankelijkheid:Closed

Reviewstatus:Peer-reviewed