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Octrooi
Prodrugs of fluorinated acyclic nucleoside phosphonates
The present invention relates to novel phosphonoamidate prodrugs of acyclic nucleoside phosphonates with a 3-fluoro-2-(phosphonomethoxy)propyl side chain. The invention also relates to the use of these novel phosphonate-modified nucleosides to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with viruses such as the hepatitis B virus, the human immunodeficiency virus, the human cytomegalovirus and the varicella zoster virus.
Octrooi-publicatienummer: EP3515923
Jaar aanvraag: 2017
Jaar toekenning: 2020
Jaar van publicatie: 2019
Status: Aangevraagd
URI: link to Espacenet
Technologiedomeinen: Farmaceutische producten
Gevalideerd voor IOF-sleutel: Ja
Toegewezen aan: Associatie KULeuven