Onderzoeker
Lies De Bock
- Disciplines:Medicinale producten, Farmacognosie en fytochemie, Farmaceutica, Ontdekking en evaluatie van biomarkers, Andere farmaceutische wetenschappen, Ontdekking en evaluatie van geneesmiddelen, Toxicologie en toxinologie, Farmacotherapie, Farmacologie
Affiliaties
- Vakgroep Bioanalyse (Departement)
Lid
Vanaf1 sep 2008 → 31 mrt 2015
Publicaties
1 - 10 van 20
- Maturation of hepatic cytochrome P450 enzymes in conventional pigs : the added value of proteomics(2018)
Auteurs: Joske Millecam, Laura De Clerck, Elisabeth Govaert, Mathias Devreese, Elke Gasthuys, Wim Schelstraete, Dieter Deforce, Lies De Bock, Stanislas Sys
Aantal pagina's: 1 - The ontogeny of cytochrome P450 enzyme activity and protein abundance in conventional pigs in support of preclinical pediatric drug research(2018)
Auteurs: Joske Millecam, Laura De Clerck, Elisabeth Govaert, Mathias Devreese, Elke Gasthuys, Wim Schelstraete, Dieter Deforce, Lies De Bock, Stanislas Sys
- Strategies for determining correct cytochrome P450 contributions in hepatic clearance predictions : in vitro-in vivo extrapolation as modelling approach and tramadol as proof-of concept compound(2017)
Auteurs: Huybrecht T'jollyn, Jan Snoeys, Lies De Bock, Pieter Annaert, Achiel Van Peer, Karel Allegaert, Geert Mannens, An Vermeulen, Koen Boussery
Pagina's: 537 - 543 - The ontogeny of hepatic CYP3A, CYP2C and CYP2E enzyme activity in conventional pigs(2015)Volume: 38
Auteurs: Joske Millecam, Mathias Devreese, Lies De Bock, Jan Van Bocxlaer, Elke Gasthuys, Patrick De Backer, Siska Croubels, Jim Riviere, Johanna Fink-Gremmels
Pagina's: 48 - 49 - Microsomal protein per gram of liver (MPPGL) in paediatric biliary atresia patients(2014)
Auteurs: Lies De Bock, Koen Boussery, Ruth De Bruyne, Myriam Van Winckel, Xavier Stephenne, Etienne Sokal
Pagina's: 308 - 312 - Pharmacokinetics in children with liver disease : can ex vivo obtained population-specific CYP450 characteristics bridge the knowledge gap?(2014)
Auteurs: Lies De Bock
- Enzymatic tumour tissue digestion coupled to SPE-UPLCU+2013tandem mass spectrometry as a tool to explore paclitaxel tumour penetration(2014)
Auteurs: Pieter Colin, Lieselotte De Smet, Lies De Bock, Koen Boussery, Chris Vervaet
Pagina's: 119 - 125 - The mycotoxin T-2 inhibits hepatic cytochrome P4503A activity in pigs(2013)
Auteurs: Joline Goossens, Lies De Bock, Ann Osselaere, Elin Verbrugghe, Mathias Devreese, Koen Boussery, Patrick De Backer
Pagina's: 54 - 56 - Development and validation of a fast and uniform approach to quantify U+03B2-lactam antibiotics in human plasma by solid phase extraction-liquid chromatography-electrospray-tandem mass spectrometry(2013)
Auteurs: Pieter Colin, Lies De Bock, Huybrecht T'jollyn, Koen Boussery
Pagina's: 285 - 293 - In vitro cytochrome P450 activity decreases in children with high paediatric end-stage liver disease scores(2013)
Auteurs: Lies De Bock, Koen Boussery, Myriam Van Winckel, Xavier Stephenne, Etienne Sokal
Pagina's: 390 - 397