Publicaties

UNLABELLED: This study evaluated six orthogeriatric care models for older fracture patients in Belgium. Integrated care on surgical wards reduced emergency department visits, while consultation on request on geriatric wards yielded the highest survival. All models had comparable costs except for integrated care on a geriatric ward, which was more expensive. PURPOSE: This study assessed the (cost-)effectiveness of systematic collaboration ...

Poorly executed care transitions from hospital to home can result in adverse outcomes, such as incorrect treatments, medication errors, patient dissatisfaction, rehospitalization, emergency department visits, and mortality. Integrated care services may improve the quality of these transitions, particularly for older, chronically ill patients who frequently move between care settings. This study aimed to (1) assess health-related quality of life ...

BACKGROUND: Comprehensive geriatric assessment (CGA) has demonstrated numerous benefits in older patients with cancer, and is internationally recommended, but more data are needed on its impact on quality of life (QoL). The aim of the G-oncoCOACH study is to evaluate the effectiveness of CGA on QoL in older patients with solid tumours receiving systemic therapy by integrating a geriatric team for implementing geriatric assessment (GA)-based ...

BACKGROUND: Currently, there is insufficient evidence supporting geriatric home rehabilitation after hospital discharge. Some studies demonstrate a positive effect, but meta-analytic evidence demonstrates uncertainty on the magnitude of the expected effect. Yet, evidence from other populations indicates that home rehabilitation could also be an effective strategy for older persons. Therefore, we aim to evaluate the effectiveness of geriatric ...

BACKGROUND: Falls among people aged 65 years and older represent a global health challenge, with substantial morbidity, mortality and economic costs. Despite strong evidence supporting the efficacy of multifactorial falls prevention interventions, their implementation in community settings remains inconsistent. There is a need to systematically develop and proactively tailor multifactorial falls prevention interventions and implementation ...

INTRODUCTION: Respiratory syncytial virus (RSV) is an important pathogen in infants, children, older adults, and those with comorbidities. Mechanisms involving viral proteins appear to underlie the ability of RSV to evade and modulate host immunity. We aimed to understand virus- and host-dependent factors regulating the development and severity of RSV infection, as related to the prevention and treatment of RSV-associated disease in adults, ...

BACKGROUND/OBJECTIVES: Accurate assessment of physical activity is essential in hospital settings, but difficult for geriatric rehabilitation patients who have slow walking speed and rely on walking aids. This study conducted an external validation of the MOX activity monitor accuracy in distinguishing between sedentary (lying, sitting), standing, and dynamic activities among hospitalized geriatric rehabilitation patients. Additionally, the ...

BACKGROUND: Frailty screening instruments are increasingly studied as risk predictors for adverse postoperative outcomes. However, because of the lack of comparative research, it is unclear which screening instrument performs best. This study therefore compared the diagnostic accuracy of seven frailty screening instruments for adverse postoperative outcomes in patients aged ≥70 years undergoing colorectal surgery. METHODS: We conducted a ...

INTRODUCTION: Older adults face a higher risk of vancomycin-related toxicity given their (patho)-physiological changes, making early management of supratherapeutic exposure crucial. Yet, data on vancomycin exposure in older adults is scarce. This study aims to compare vancomycin concentrations between older and younger patients, emphasizing supratherapeutic concentrations and the effect of patient characteristics. METHODS: This observational ...

BACKGROUND: In Northwestern Switzerland, recent legislation tackles the needs of community-dwelling older adults by creating Information and Advice Centers (IACs). IACs are a new service in the community that aims to assess the needs and provide information on age-related issues to community-dwelling older adults and their families. Previous studies reported difficulties in reaching community-dwelling older adults for community-based programs. ...