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Molecular characterization of diarrheagenic Escherichia coli isolates from children with diarrhea: a cross-sectional study in four provinces of Mozambique diarrheagenic Escherichia coli in Mozambique Instituut voor Tropische Geneeskunde

Lena Vania Manhique-Coutinho, Paola Chiani, Valeria Michelacci, Elisa Taviani, Adilson Fernando Loforte Bauhofer, Assucenio Chissaque, Idalecia Cossa-Moiane, Julia Assiat Monteiro Sambo, Jorfelia J. Chilaule, Esperanca Lourenco Guimaraes, et al.

Objectives: Analyze the frequency of diarrheagenic Escherichia coli (DEC) pathotypes and their antimicrobial resistance profiles among children aged

Methods: A cross-sectional hospital-based surveillance program of diarrhea was implemented in Maputo, Sofala, Zambezia, and Nampula. A single stool sample was collected from each child from May 2014 to May 2017. Culture methods and biochemical characterization were performed to detect E. ...

High frequency of Cryptosporidium hominis infecting infants points to a potential anthroponotic transmission in Maputo, Mozambique Instituut voor Tropische Geneeskunde

Idalecia Cossa-Moiane, Herminio Cossa, Adilson Fernando Loforte Bauhofer, Jorfelia J. Chilaule, Esperanca Lourenco Guimaraes, Diocreciano Matias Bero, Marta Cassocera, Miguel Bambo, Elda Muianga Anapakala, Assucenio Chissaque, et al.

Cryptosporidium is one of the most important causes of diarrhea in children less than 2 years of age. In this study, we report the frequency, risk factors and species of Cryptosporidium detected by molecular diagnostic methods in children admitted to two public hospitals in Maputo City, Mozambique. We studied 319 patients under the age of five years who were admitted due to diarrhea between April 2015 and February 2016. Single stool samples ...

Whole genome characterization and evolutionary analysis of G1P[8] rotavirus A strains during the pre- and post-vaccine periods in Mozambique (2012-2017) Instituut voor Tropische Geneeskunde

Benilde Munlela, Eva D. Joao, Celeste M. Donato, Amy Strydom, Simone S. Boene, Assucenio Chissaque, Adilson F. L. Bauhofer, Jeronimo Langa, Marta Cassocera, Idalecia Cossa-Moiane, et al.

Mozambique introduced the Rotarix(R) vaccine (GSK Biologicals, Rixensart, Belgium) into the National Immunization Program in September 2015. Although G1P[8] was one of the most prevalent genotypes between 2012 and 2017 in Mozambique, no complete genomes had been sequenced to date. Here we report whole genome sequence analysis for 36 G1P[8] strains using an Illumina MiSeq platform. All strains exhibited a Wa-like genetic backbone ...

Risk Factors and Circulating Subtypes of Cryptosporidium spp. and Giardia duodenalis in Hospitalized Children in Mozambique Instituut voor Tropische Geneeskunde

OL Nhambirre, ML Lobo, I Cossa-Moiane, Adilson F. L. Bauhofer, Nilsa de Deus, O Matos
Cryptosporidium spp. and Giardia duodenalis are important diarrheal agents in children in developing countries. Little is known about their molecular epidemiology; as such, the objective of this study was to determine the risk factors and genetic diversity of both parasites in diarrheal samples in Mozambique. In this study, two nested PCRs targeting ssurRNA and gp60 genes were used for genetic diversity of Cryptosporidium spp. and b-giardin for ...

Respectful maternity care and the role of male partners in Mozambique : practices, obstacles and conceptualisation Universiteit Gent

Anna Galle
Maternal health is a constant concern in Mozambique, as the nation’s maternal mortality rate (MMR) is still one of the highest in the world. The latest numbers from 2017 indicate a MMR of 289 maternal deaths per 100 000 livebirths[130]. On a more positive note, significant progress has been made in the country in encouraging women to deliver in health facilities, with a nationwide institutional delivery rate of 70% [113]. In line with global ...

Maternal death and delays in accessing emergency obstetric care in Mozambique Universiteit Hasselt Universiteit Gent KU Leuven

Osvaldo LOQUIHA, Marc AERTS
Background: Despite declining trends maternal mortality remains an important public health issue in Mozambique. The delays to reach an appropriate health facility and receive care faced by woman with pregnancy related complications play an important role in the occurrence of these deaths. This study aims to examine the contribution of the delays in relation to the causes of maternal death in facilities in Mozambique. Methods: Secondary analysis ...

Seroprevalence of transfusion-transmissible infections and evaluation of the pre-donation screening performance at the Provincial Hospital of Tete, Mozambique Instituut voor Tropische Geneeskunde

J Stokx, P Gillet, Anja De Weggheleire, EC Casas, R Maendaenda, AJ Beulane, IV Jani, SOLON KIDANE, CD Mosse, Jan Jacobs, et al.
BACKGROUND: The World Health Organization recommends universal and quality-controlled screening of blood donations for the major transfusion-transmissible infections (TTIs): human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis. The study objectives were to determine the seroprevalence of these TTIs among blood donors at the Provincial Hospital of Tete, Mozambique, and to assess the local pre-donation ...

Intestinal parasites in children up to 14 years old hospitalized with diarrhea in Mozambique, 2014-2019 Instituut voor Tropische Geneeskunde

OL Nhambirre, Idalecia Cossa Moiane, Adilson F. L. Bauhofer, Assucenio Chissaque, ML Lobo, O Matos, Nilsa de Deus
Diarrhea remains a public health problem in Mozambique, even with control strategies being implemented. This analysis aimed to determine the proportion and factors associated with intestinal parasitic infection (IPI) in children up to 14 years old with diarrheal disease, in the southern, central and northern regions of Mozambique. A single diarrheal sample of 1424 children was collected in hospitals and examined using the formol-ether ...