Publicaties

Introduction: Vectorcardiographic (VCG) QRS area of left bundle branch block (LBBB) predicts acute hemodynamic response in cardiac resynchronization therapy (CRT) patients. We hypothesized that changes in QRS area occurring with biventricular pacing (BV) might predict acute hemodynamic CRT response (AHR). Methods and Results: VCGs of 624 BV paced electrocardiograms (25 LBBB patients with 35 different pacing configurations) were calculated ...

Objective of this experience report is to address specific issues regarding standard SAP ERP implementation in a medical institution. Target Company is a state owned health care institution from Bosnia and Herzegovina. Report will treat selected issues which could trouble standard SAP ERP implementation trough predefined ERP implementation methodology for SAP ERP. This report presents observations/ remarks based on experience of authors in ...

Objective: Antibiotics are prescribed too often in acutely ill children in primary care. We examined whether a Point-of-Care (POC) C-reactive Protein (CRP) test influences the family physicians' (FP) prescribing rate and adherence to the Evidence Based Medicine (EBM) practice guidelines. Design: Cluster randomized controlled trial. Setting: Primary care, Flanders, Belgium. Intervention: Half of the children with non-severe acute infections ...

Steel with a nominal composition of 0.25C-1.5Si-3Mn-0.023Al (mass %) was subjected to Quenching and Partitioning (Q&P) with varying parameters (quenching temperature, partitioning temperature and partitioning time) resulting in formation of multi-phase microstructure, which was thoroughly studied using X-ray (XRD) and Electron Backscatter Diffraction (EBSD). Mechanical properties of the Q&P steel were measured by tensile tests. Plastic ...

Requirements Engineering (RE) is the basis for efficient software implementation and quality management. Tools which support RE in general are numerous nowadays; however, the task of providing a tool that specializes in RE for dynamic, customizable service-centric systems (like ERP systems) has been addressed rarely. According to this we proposed an artifact in a form of software functionalities list derived from performing literature review and ...

Background: Measurements of QRS duration (QRSD) in patients undergoing cardiac resynchronization therapy (CRT) are not standardized. We hypothesized that both the measurement of QRSD and its predictive value on CRT response are sensitive to the method by which QRSD is measured. Methods: Electrocardiograms (ECGs) pre- and post-CRT from 52 CRT patients (66 +/- 12 years, 65% male) were retrospectively analyzed. Custom-made software was developed to ...

Objectives The goal of this study was to examine the relative impact of QRS morphology and duration in echocardiographic responses to cardiac resynchronization therapy (CRT) and clinical outcomes. Background At least one-third of all patients treated with CRT fail to derive benefit. Patients without left bundle branch block (LBBB) or patients with smaller QRS duration (QRSd) respond less or not at all to CRT. Methods We retrospectively assessed ...

© 2015 Elsevier Inc. All rights reserved. TRP channels are important in the maintenance of the normal cellular homeostasis, monitor the external and internal environment sensing various physical and chemical stimuli, and also play a significant role in the pathomechanism of various acquired and inherited diseases. In the last decade, an emerging number of mutations in the 28 mammalian TRP channel coding genes were described as a primary cause of ...

Manufacturing Resource Planning (MRP) is a widely used approach through manufacturing environments in a variety of sectors. With a tendency to go to specialized, smaller lot sizes in several industries (e.g., the pharmaceutical sector), companies are dealing with capacity bottlenecks if the planning rhythm wheel is not well calibrated or when production lines are not flexible enough in terms of changeover (C/O) and set-up times (S/U) (OEE is too ...

Enterprise Resource Planning (ERP) implementation is a complex and vibrant process, one that involves a combination of technological and organizational interactions. Often an ERP implementation project is the single largest IT project that an organization has ever launched and requires a mutual fit of system and organization. Also the concept of an ERP implementation supporting business processes across many different departments is not a ...