Publicaties

With the increasing impact of computers on society, we are faced with the obligation of maintaining increasingly complex software systems. Thiscomplexity makes it difficult to verify whether the actual behavior corresponds to the intended behavior. This creates an ever increasing need for inspection. However, this is far from trivial, as information about the run-time state and behavior is distributed over different machines and different ...

Objective Systemic juvenile idiopathic arthritis (sJIA) is unique among rheumatic diseases of childhood, given its distinctive systemic inflammatory character. Inappropriate control of innate immune responses following an initially harmless trigger is thought to account for the excessive inflammatory reaction in patients. We aimed to generate a similar systemic inflammatory syndrome in mice by injection of a relatively innocuous, yet persistent ...

The equation of motion for the reduced Wigner function of a system coupled to an external quantum system is presented for the specific case when the external quantum system can be modeled as a set of harmonic oscillators. The result is derived from the Wigner function formulation of the Feynman-Vernon influence functional theory. It is shown how the true self-energy for the equation of motion is connected with the influence functional for the ...

Starting from Feynmans Lagrangian description of quantum mechanics, we propose a method to construct explicitly the propagator for the Wigner distribution function of a single system. For general quadratic Lagrangians, only the classical phase space trajectory is found to contribute to the propagator. Inspired by Feynmans and Vernons influence functional theory we extend the method to calculate the propagator for the reduced Wigner function of a ...

© The Author(s) 2019. Care pathway implementation is characterised by a dual complexity. A care pathway itself represents a complex intervention with multiple interacting and interdependent intervention components and outcomes. The organisations in which care pathways are being implemented represent complex systems that need to be directed at change through an in-depth understanding of their external and internal context in which they are ...