Use of pressure drop profiles to assess the accuracy of total pore blocking measurements of the external porosity of chromatographic columns Vrije Universiteit Brussel
By comparing the pressure drop in a column where the meso-pores of the particles have been blocked using the Total Pore Blocking (TPB) method to measure the interstitial volume of the column with that in the same column when the particle meso-pores are fully open, it could be demonstrated in a very sensitive way that the interstitial volume is completely devoid of any significant amount of remaining pore blocking agent in the final phase of a ...