Publicaties
Getting the Most out of Spirometry: A Tool to Guide Dry Powder Inhaler Use Vrije Universiteit Brussel
Effect of laryngeal jet on dry powder inhaler aerosol deposition: a numerical simulation KU Leuven
Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study Vrije Universiteit Brussel
New treatment strategies are needed to improve airway clearance and reduce the morbidity and the time burden associated with cystic fibrosis (CF).
OBJECTIVES:
To determine whether long-term treatment with inhaled mannitol, an osmotic agent, improves lung function and morbidity.
METHODS:
Double-blind, randomized, controlled trial of inhaled mannitol, 400 mg twice a day (n = 192, "treated" group) or 50 mg twice ...
Inhaled dry powder mannitol in children with cystic fibrosis Vrije Universiteit Brussel KU Leuven
INTRODUCTION: Inhaled mannitol has beneficial effects on lung function, mucociliary clearance, quality of life and sputum properties. This trial examined the efficacy of inhaled mannitol in children with cystic fibrosis (CF).
METHODS: The efficacy of inhaled mannitol in children with CF aged 6-17years was assessed in a phase 2, randomised, placebo-controlled crossover study. Subjects were randomly assigned to mannitol 400mg every 12h ...
Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study KU Leuven
Development and evaluation of well-tolerated and tumor-penetrating polymeric micelle-based dry powders for inhaled anti-cancer chemotherapy KU Leuven
New developments in inhaler devices within pharmaceutical companies Vrije Universiteit Brussel KU Leuven
BACKGROUND: Pharmaceutical companies offer an increasing number of inhaler devices, whether or not together with new substances, for maintenance treatment of patients with COPD or asthma. However, well-designed studies to support these developments are scarce.
OBJECTIVES: The aim of this research was to evaluate how far new developments of inhaler devices are scientifically supported and translate into improvements of patient ...