Publicaties
Dust mite allergy in discussion : early diagnosis, better treatment Universiteit Gent
Multiomics and spatial mapping characterizes human CD8+T cell states in cancer KU Leuven
Correction: Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop Vrije Universiteit Brussel KU Leuven
(Cancer Cell 40, 1600–1618; December 12, 2022) In this article, the authors demonstrated that antiangiogenic immunotherapies differentiate postcapillary venules into high-endothelial venules (HEVs) that foster permissive TCF1 + T lymphocyte niches. In the introduction, they mistakenly stated that HEVs express L-Selectin/CD62L, while HEVs express the sulphated and glycosylated ligands for L-Selectin/CD62L. The original article has been ...
Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop Vrije Universiteit Brussel KU Leuven Vlaams Instituut voor Biotechnologie
The lack of T cell infiltrates is a major obstacle to effective immunotherapy in cancer. Conversely, the formation of tumor-associated tertiary-lymphoid-like structures (TA-TLLSs), which are the local site of humoral and cellular immune responses against cancers, is associated with good prognosis, and they have recently been detected in immune checkpoint blockade (ICB)-responding patients. However, how these lymphoid aggregates develop ...