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Prostatic calculi : relationship to chronic prostatitis and treatment options. A critical analysis = Οι ασβεστώσεις του προστάτη, η σχέση τους με την χρόνια προστατίτιδα και η αντιμετώπισή τους. Μια κριτική ανάλυση Universiteit Gent
While prostatic calculi are a common ultrasound finding, their exact prevalence of is not known. It has been reported to vary widely, from 7% to 70% with greater incidences occurring in chronic prostatitis patients. However, pathophysiology, clinical relevance and association of prostatic calculi with prostatic diseases remain unclear. Traditionally they considered to be a random finding of no clinical significance probably associated with ...
Dutasteride for the prevention of prostate cancer in men with high-grade prostatic intraepithelial neoplasia: results of a phase III randomized open-label 3-year trial KU Leuven
High-grade prostatic intraepithelial neoplasia (HGPIN) is a potential precursor of prostate cancer (PCa), and patients with HGPIN are at high risk for PCa development. Objective of our study was to evaluate the efficacy of dutasteride 0.5 mg in PCa prevention among men with isolated HGPIN on biopsy.
What is the Need for Prostatic Biomarkers in Prostate Cancer Management? KU Leuven
Discriminating patients with a low risk of progression from those with lethal prostate cancer is one of the main challenges in prostate cancer management. Indeed, such discrimination is essential if we aim to avoid overtreatment in men with indolent disease and to improve survival in those men with lethal disease. We are reporting on the current literature on such prognostic tools that are now available, their clinical role and their limitations ...
Multicenter optimization and validation of a 2-gene mRNA urine test for detection of clinically significant prostate cancer before initial prostate biopsy Universiteit Gent
Purpose: A 2-gene, urine based molecular test that combines mRNA biomarkers with clinical factors can risk stratify patients for clinically significant prostate cancer. To ensure the generalizability of assay results we optimized and validated the clinical model for men with serum prostate specific antigen less than 10 ng/ml who were undergoing initial prostate biopsy. Materials and Methods: Urine samples were collected from 1,955 men from The ...