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Long-Term MALT1 Inhibition in Adult Mice Without Severe Systemic Autoimmunity. Vlaams Instituut voor Biotechnologie Universiteit Gent
Sodium chloride triggers Th17 mediated autoimmunity Vlaams Instituut voor Biotechnologie Universiteit Hasselt
MicroRNAs: markers of β-cell stress and autoimmunity. KU Leuven
PURPOSE OF REVIEW: We discuss current knowledge about microRNAs (miRNAs) in type 1 diabetes (T1D), an autoimmune disease leading to severe loss of pancreatic β-cells. We describe: the role of cellular miRNAs in regulating immune functions and pathways impacting insulin secretion and β-cell survival; circulating miRNAs as disease biomarkers. RECENT FINDINGS: Studies examined miRNAs in experimental models and patients, including analysis of ...
Thyroid Autoimmunity and Intracytoplasmic Sperm Injection Outcome: A Systematic Review and Meta-Analysis KU Leuven
Background: Since 2010, three meta-analyses have been published on the impact of thyroid autoimmunity (TAI) on pregnancy outcomes in infertile women treated with assisted reproductive technology (ART). The initially observed high risk of miscarriage became very low in the most recent meta-analysis published in 2016. Objective: To investigate whether the lower risk of miscarriage in the latest meta-analysis was associated with the increased use ...
A kindred with mutant IKAROS and autoimmunity Vlaams Instituut voor Biotechnologie KU Leuven
Efficacy of mycophenolate on lung disease and autoimmunity in children with immunodeficiency KU Leuven
The autoimmune manifestations of primary immunodeficiencies, such as autoimmune lymphoproliferative syndrome (ALPS) and common variable immunodeficiency (CVID), often constitute a great therapeutic challenge and have a significant impact on patients' morbidity and mortality. The most common autoimmune presentations are autoimmune cytopenias, but organ-related autoimmunity is also frequently observed. From a pulmonology perspective, ...
Immunometabolic Regulation of Interleukin-17-Producing T Helper Cells: Uncoupling New Targets for Autoimmunity Vlaams Instituut voor Biotechnologie Universiteit Hasselt
Impact of thyroid autoimmunity on cumulative delivery rates in in vitro fertilization/intracytoplasmic sperm injection patients Vrije Universiteit Brussel
OBJECTIVE: To predict the impact of thyroid autoimmunity (TAI) on the probability of delivery after a defined number of treatment cycles, using analysis of cumulative delivery rates in patients with and without TAI.
DESIGN: Retrospective cohort study performed at the Center for Reproductive Medicine and Department of Endocrinology, University Hospital of Brussels, approved by the institutional review board of the hospital.
...Lpr-induced systemic autoimmunity is unaffected by mast cell-deficiency KU Leuven
The function of mast cells in allergic and organ-specific autoimmune responses is highly controversial. In the current study we aimed to dissect the role of mast cells in systemic autoimmunity in the B6(lpr/lpr) mouse, a spontaneous model of systemic lupus erythematosus. B6(lpr/lpr) mice were interbred with C57Bl/6-Kit(W-sh/W-sh) (Wsh) mice, resulting in mast cell-deficiency. The offspring from this cross (Lpr/Wsh mice) developed symptoms of ...