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The impact of autologous platelet concentrates on endodontic healing : a systematic review Universiteit Gent KU Leuven
The current literature was reviewed to determine the impact of autologous platelet concentrates (APCs) on endodontic healing. All types of clinical study designs concerning any kind of endodontic treatment involving the application of APCs were included. Two independent reviewers searched three databases (PubMed, Embase, and Cochrane Library) for studies, complemented by hand search, until 16/1/2016. From the 423 identified records, 48 articles ...
Regenerative potential of platelet concentrates in periodontal surgery KU Leuven
Regeneration is an emerging field in medicine. Current regenerative methods in periodontics include the use of autografts, allografts, alloplasts, or xenografts and naturally derived synthetic membranes that are either bioresorbable or nonresorbable. In the last twenty years, platelet concentrates (PCs) have emerged as a potential regenerative method in Oral and Maxillofacial Surgery, used as a sole filling material or as scaffold. Its purpose ...
The contribution of von Willebrand factor-GPIbα interactions to persistent aggregate formation in apheresis platelet concentrates KU Leuven Universiteit Gent
© 2016 International Society of Blood Transfusion. Background and Objectives: Apheresis platelet concentrates sometimes contain persistent aggregates (PA). Because apheresis involves extracorporeal circulation, we hypothesized that interactions between GPIbα and von Willebrand factor (VWF) underlie their origin. Materials and Methods: Platelets in donations with PA were compared to aggregate-free (AF) controls. Flow cytometry was used to ...
Riboflavin and amotosalen photochemical treatments of platelet concentrates reduce thrombus formation kinetics in vitro KU Leuven Universiteit Gent
© 2014 International Society of Blood Transfusion. Background: Photochemical treatment (PCT) of platelet concentrates using photosensitizers and ultraviolet light illumination reduces the proliferation potential of pathogens by damaging biomolecules. Materials and Methods: The impact of riboflavin (RF-PRT)- and amotosalen (AS-PCT)-based pathogen inactivation on platelets was studied using microfluidic flow chambers on immobilized collagen using ...
The impact of autologous platelet concentrates on endodontic healing: a systematic review KU Leuven
The current literature was reviewed to determine the impact of autologous platelet concentrates (APCs) on endodontic healing. All types of clinical study designs concerning any kind of endodontic treatment involving the application of APCs were included. Two independent reviewers searched three databases (PubMed, Embase, and Cochrane Library) for studies, complemented by hand search, until 16/1/2016. From the 423 identified records, 48 articles ...
Comparison of three commercially available buffy coat pooling sets for the preparation of platelet concentrates Universiteit Gent
Persistent aggregates in apheresis platelet concentrates are commonly collected from donors with a history of aggregate donation Universiteit Gent KU Leuven
Persistent aggregates in apheresis platelet concentrates KU Leuven Universiteit Gent
© 2015 International Society of Blood Transfusion. Background: Aggregates often appear during apheresis. Sometimes, these persist throughout storage, causing product wastage. This study assessed product quality of apheresis concentrates containing persistent aggregates (PA) and aimed to identify the factors that contribute to their formation. Methods: Donation (n = 180) and platelet indices (n ≥ 10) from apheresis concentrates with PA were ...