< Back to previous page
Organisation
Laboratory of Synapse Biology (VIB-KU Leuven)
Lab
Main organisation:Research Group Molecular Neurobiology (VIB-KU Leuven)
Lifecycle:1 Jan 2013 → Today
Organisation profile:
The Laboratory of Synapse Biology aims to unravel the molecular mechanisms that control neuronal connectivity in developing circuits, and determine how perturbations in this process affect cognitive function.
Keywords:Synapse
Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Current researchers
1 - 10 of 16 results
- Lucas Baltussen (Member)
- Stephanie Chanda (Member)
- Danie Daaboul (Member)
- Dan Dascenco (Member)
- Cydric Geyskens (Member)
- Artemis Koumoundourou (Member)
- Elke Leysen (Member)
- Blanca Lorente Echeverría (Member)
- Gabriele Marcassa (Member)
- Beatriz Marques (Member)
Projects
1 - 10 of 43
- Synaptic signatures: Understanding thalamocortical circuit specification and disease vulnerabilityFrom1 Nov 2025 → TodayFunding: FWO junior postdoctoral fellowship
- Targeting synaptic dysfunction in dementiaFrom1 Oct 2025 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- The role of presynaptic protein Brinp2 in the maintenance of neuronal homeostasis and synaptic plasticityFrom27 Jun 2025 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Synaptic Signatures and Disease Vulnerabilities in Layer 5 Pyramidal NeuronsFrom18 Mar 2025 → TodayFunding: Foundations, funds and other with scientific goal
- Deciphering molecular and functional specificity in thalamocortical and corticocortical synaptic circuitsFrom1 Jan 2025 → TodayFunding: FWO research project (including WEAVE projects)
- Cell-surface receptor-mediated control of postsynaptic organelle distribution in synaptic plasticity and experience-dependent dendritic spine maturation.From1 Jan 2025 → TodayFunding: FWO research project (including WEAVE projects)
- Synaptic signatures: Understanding thalamocortical circuit specification and disease vulnerabilityFrom1 Jan 2025 → TodayFunding: Other federal public and semi-governmental institutions
- Role of the GPR158 receptor in regulating organelle distribution in synaptic plasticityFrom16 Sep 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Fast mesoscale volumetric imaging of live and fixed large samples and whole organismsFrom1 May 2024 → TodayFunding: BOF - scientific equipment program
- Enhancer-AI: AI-driven modelling and design of cell type specific enhancers for gene therapyFrom1 Oct 2023 → TodayFunding: FWO Strategic Basic Research (SBO)
Publications
41 - 50 of 86
- RNA Granules at the Crossroads of Synaptic Dysfunction and Neurodegeneration.(2025)Published in: JOURNAL OF NEUROCHEMISTRYISSN: 0022-3042Issue: 11Volume: 169Pages: e70269
- Synaptic signatures and disease vulnerabilities of layer 5 pyramidal neurons(2025)Published in: NATURE COMMUNICATIONSISSN: 2041-1723Issue: 1Volume: 16
- The cross-modal aspect of mouse visual cortex plasticity induced by monocular enucleation is age dependent(2014)Published in: Journal of Comparative NeurologyISSN: 0021-9967Issue: 4Volume: 522Pages: 950 - 970
- Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors(2018)Published in: Cell ReportsISSN: 2211-1247Issue: 1Volume: 25Pages: 130 - +
- The sorting receptor SorCS1 controls axonal targeting of neurexin(2016)
- Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision(2015)Published in: Progress in Neuro-Psychopharmacology & Biological PsychiatryISSN: 0278-5846Volume: 59Pages: 49 - 58
- Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease(2024)Published in: ScienceISSN: 0036-8075Issue: 6699Volume: 384
- Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation(2021)Published in: NeuronISSN: 0896-6273Issue: 5Volume: 109
- Distinct and simultaneously active plasticity mechanisms in mouse hippocampus during phases of Morris water maze training(2015)Published in: Brain Structure and FunctionISSN: 1863-2653Issue: 3Volume: 220Pages: 1273 - 1290
- Specification of synaptic connectivity by cell surface interactions(2016)Published in: Nature Reviews. NeuroscienceISSN: 1471-003XIssue: 4Volume: 17Pages: 22 - 35