Organisation
Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven)
Division
The Lab of Molecular Oncology and Angiogenesis aims to shed light on the genetic and molecular mechanisms that regulate vessel shape remodeling and endothelial cell fate, with the overall aim of defining alternative therapeutic opportunities to improve anti-cancer therapy, as well as therapeutic angiogenesis for revascularization of ischemic tissues.
Current researchers
1 - 7 of 7 results
- Max Mazzone (Responsible)
- Emanuele Berardi (Member)
- Marie-Pauline Orban (Member)
- Carla Riera Domingo (Member)
- Silvia Rivis (Member)
- Tommaso Scolaro (Member)
- Shikang Zhao (Member)
Projects
1 - 10 of 68
- Targeting the DNA methylation profile of cytotoxic T cells to overcome immunotherapy resistance of pancreatic cancerFrom5 Mar 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding glutamate metabolism in the tumor microenvironment to tackle Immune Checkpoint Blockade (ICB) resistanceFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Role of SLC1A3 in tumor-associated macrophages during immunotherapy resistance onset in breast cancerFrom1 Oct 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Targeting the CDA/P2Y6 axis to overcome immunosuppression and favor response to immune checkpoint inhibitors in pancreatic cancerFrom1 Jul 2023 → TodayFunding: Other federal public and semi-governmental institutions
- Tackling tumor immunosuppression by reprograming eicosanoid metabolism and signaling in the tumor microenvironmentFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Tackling SLC1A3 in tumor-associated macrophages to overcome anti-PD1 immunotherapy resistance in breast cancerFrom31 Oct 2022 → TodayFunding: FWO Strategic Basic Research Grant
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- BD Imaging Cell Sorter – BD Cell View TechnologyTMFrom24 Jun 2022 → TodayFunding: Other federal scientific institutions
- Tricking tumor immunosuppression: RNA epigenetics as novel target to improve cancer immunotherapyFrom1 Jan 2022 → TodayFunding: FWO EOS
- Duchenne muscular dystrophy.From1 Jan 2022 → 31 Dec 2022Funding: Nonprofit institution or equivalents
Publications
31 - 40 of 314
- Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties(2013)
Authors: Frederik De Smet, Katrien De Bock, Maria Georgiadou, Annelii Ny, Max Mazzone, Filip Claes, Koen Poesen, Diether Lambrechts, Marlies Van de Wouwer, Ann Van Schepdael, et al.
Pages: 477 - 488 - Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers(2022)
Authors: Ali Talebi, Wout De Wispelaere, Regina Esi Mensimah Baiden-Amissah, Guy Eelen, Emanuele Berardi, Johan Swinnen, Peter Carmeliet, Diether Lambrechts, Sarah-Maria Fendt, Daniela Annibali, et al.
- A noninterfering system to measure in-cage spontaneous physical activity in mice.(2018)
Authors: Chiel Poffé, Sebastiaan Dalle, Hans Kainz, Emanuele Berardi, Peter Hespel
Pages: 263 - 270 - Impact of Immunometabolism on Cancer Metastasis: A Focus on T Cells and Macrophages(2020)
Authors: Nina Flerin, Ria Pinioti
- Metabolic traits ruling the specificity of the immune response in different cancer types(2021)
Authors: Federica Cappellesso, Samantha Pretto, Max Mazzone
Pages: 124 - 143 - Neutrophils enhance early Trypanosoma brucei infection onset(2018)
Authors: Max Mazzone
- Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus(2015)
Authors: Hans Prenen, Séverine Vermeire, Isabelle Cleynen, Raf Bisschops
Pages: 367 - 378 - Tumor-associated macrophages: a short compendium(2019)
Authors: Hans Prenen, Max Mazzone
Pages: 1447 - 1458 - Hypomagnesaemia and targeted anti-epidermal growth factor receptor (EGFR) agents(2011)
Authors: Sabine Tejpar, Hans Prenen, Eric Van Cutsem
Pages: 227 - 233 - Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis(2015)
Authors: Linde De Smedt, Olivier Govaere, Thomas Tousseyn, Eric Van Cutsem, Hans Prenen, Sabine Tejpar, Gert Matthijs, Xavier Sagaert
Pages: 500 - 9