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Researcher
Kim De Keersmaecker
- Disciplines:Cancer biology
Affiliations
- Laboratory for Disease Mechanisms in Cancer (Division)
Responsible
From1 Oct 2016 → Today - Laboratory for Disease Mechanisms in Cancer (Division)
Member
From1 Oct 2014 → Today - Department of Human Genetics (Department)
Member
From1 Oct 2013 → 30 Sep 2014 - Laboratory of Molecular Biology of Leukemia (VIB-KU Leuven) (Division)
Member
From1 Mar 2009 → 30 Sep 2015
Projects
1 - 10 of 42
- Raising the voice of silent mutations in cancerFrom1 Oct 2023 → TodayFunding: BOF - postdoctoral mandates
- Deregulated mRNA transcription and protein translation in the transformation of normal T-cells to malignant cells.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Serine/glycine synthesis addiction in acute lymphoblastic leukemia and resulting therapeutic opportunitiesFrom4 Jul 2021 → TodayFunding: FWO fellowships
- Serine/glycine synthesis addiction in acute lymphoblastic leukemia and resulting therapeutic opportunitiesFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- VyCAP single cell isolation platform for high-quality single-cell analysisFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- Role of -1 programmed ribosomal frameshifting dysregulation on the JAK2 oncogeneFrom25 Jul 2020 → TodayFunding: FWO fellowships
- Silent mutations in cancerFrom1 May 2020 → TodayFunding: H2020 - Frontier Research (ERC)
- The role of NKX2-1 in T-cell acute lymphoblastic leukemia and NKX2-1 cooperation with the ribosomal RPL10 R98S and NOTCH1 mutations.From1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Role of PTEN dysregulation downstream of ribosomal protein RPL5/RPL11 lesions in cancer.From1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Fidelity of translation in healthy agingFrom26 Sep 2019 → 26 Sep 2023Funding: BOF - doctoral mandates
Publications
41 - 50 of 90
- Analysis of gene expression data of RPL10 mutant T-cell leukemia by SEMsubPA(2018)
Authors: Daniele Pepe, Kim De Keersmaecker
Pages: 130 - 135Number of pages: 6 - How the RPL10 R98S mutation translates T-cell acute lymphoblastic leukemia(2017)
Authors: Tiziana Girardi, Kim De Keersmaecker
- Ribosomal proteins: a novel class of oncogenic drivers(2017)
Authors: Sergey Sulima, Kim De Keersmaecker
Pages: 89427 - 89428 - How Ribosomes Translate Cancer(2017)
Authors: Sergey Sulima, Kim De Keersmaecker
Pages: 1069 - 1087 - Low frequency mutations in ribosomal proteins RPL10 and RPL5 in multiple myeloma(2017)
Authors: Isabel Hofman, Ellen Geerdens, Lucienne Michaux, Michel Delforge, Kim De Keersmaecker
Pages: E317 - E320 - Ribosomal defects in multiple myeloma: RPL5 is a candidate tumor suppressor(2017)
Authors: Isabel Hofman, Kim De Keersmaecker
Number of pages: 158 - The genetics and molecular biology of T-ALL(2017)
Authors: Tiziana Girardi, Carmen Vicente, Jan Cools, Kim De Keersmaecker
Pages: 1113 - 1123 - The genetics and molecular biology of T-ALL(2017)
Authors: Tiziana Girardi, Carmen Vicente, Jan Cools, Kim De Keersmaecker
Pages: 1113 - 1123 - The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types(2017)
Authors: Laura Fancello, Kim Kampen, Isabel Hofman, Kim De Keersmaecker
Pages: 14462 - 14478 - Synergistic antileukemic therapies in NOTCH1-induced T-ALL(2017)
Authors: Tiziana Girardi, Kim De Keersmaecker
Pages: 2006 - 2011
Patents
1 - 3 of 3