Researcher
Marine Jean Christophe
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Morphological sciences, Oncology
- See also: Chris Marine (KU Leuven)
Affiliations
- Laboratory for Molecular Cancer Biology (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2017 → Today - VIB-KU Leuven Center for Cancer Biology (Research Center)
Responsible
From1 Jan 2017 → Today - Marine Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory for Molecular Cancer Biology (VIB-KU Leuven) (Division)
Member
From1 Oct 2013 → Today - Department of Human Genetics (Department)
Member
From1 Oct 2009 → 31 Dec 2016
Projects
1 - 10 of 10
- VIB Grant for Marine Lab_Period:2022-01-01-2026-12-31From1 Jan 2022 → TodayFunding: FRI - Project driven research
- Eradicating the minimal residual disease in melanomaFrom1 Jan 2022 → TodayFunding: Other international institutions, not mentioned elsewhere
- International PhD Programme for Medical DoctorsFrom1 Jan 2022 → TodayFunding: Other EU initiatives out of framework
- 4D TUMORMAPFrom1 Jul 2021 → 30 Jun 2022Funding: Other international institutions, not mentioned elsewhere
- Understanding resistance to immune checkpoint inhibitors by mapping the tumor-host ecosystem at single-cell resolution — cellsIMPACT - marie curie individual fellowship Joanna PozniakFrom1 May 2020 → 30 Apr 2022Funding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- 'Exploring the non-genetic (i.e. ePIgenetic) mechanisms that contribute to therapy Escape in melanoma — EscaPI - Marie curie individual fellowship Aurélie BoussardFrom1 May 2020 → 30 Apr 2022Funding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Melanoma Research alliance awardFrom1 Jun 2019 → 31 May 2022Funding: Other international institutions, not mentioned elsewhere
- Intra-tumoral heterogeneity in NRAS-driven metastatic melanoma — INHuMAN’ (marie curie individual fellowship voor Karras Panagiotis)From1 Apr 2019 → 31 Mar 2021Funding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Revolutionizing Healthcare by Tracking and Understanding Human Cells during Disease’ — ‘LifeTime’From1 Mar 2019 → 30 Apr 2020Funding: Other EU initiatives out of framework
- VIB Grant for Marine Lab_Period:2017-01-01-2021-12-31From1 Jan 2017 → 31 Dec 2021Funding: FRI - Project driven research
Publications
61 - 70 of 78
- Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma(2018)
Authors: Jean-Christophe Marine
Pages: 6174-6187 - Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018(2018)
Authors: Mathieu Bertrand, Jean-Christophe Marine, Tom Vanden Berghe, Peter Vandenabeele
Pages: 486-541 - Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy(2018)
Authors: Florian Rambow, Aljosja Rogiers, Joao Duarte, Sarah-Maria Fendt, Jean-Christophe Marine
Pages: 2500 - Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53(2018)
Authors: Jean-Christophe Marine
Pages: 594-609 e8 - The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids(2018)
Authors: Florian Rambow, Jean-Christophe Marine
Pages: 4533-4548 - Toward Minimal Residual Disease-Directed Therapy in Melanoma(2018)
Authors: Florian Rambow, Aljosja Rogiers, Oskar Marin Bejar, Sara Aibar Santos, Michael Dewaele, Panagiotis Karras, Daniel Brown, Carmen Adriaens, Stein Aerts, Jean-Christophe Marine
Pages: 843-855 e19 - The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells(2017)
Authors: Flavie Luciani, Jean-Christophe Marine
Pages: e3169 - Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma(2017)
Authors: Michael Olvedy, Flavie Luciani, Bram Boeckx, Jasper Wouters, Florian Rambow, Sara Aibar Santos, Bernard Thienpont, Jasmine Barra, Corinna Kohler, Stein Aerts, et al.
Pages: 2310-2325 - NEAT1-containing paraspeckles: Central hubs in stress response and tumor formation(2017)
Authors: Carmen Adriaens, Jean-Christophe Marine
Pages: 137-138 - Translation rewiring at the heart of phenotype switching in melanoma(2017)
Authors: Jean-Christophe Marine
Pages: 282-283
Patents
1 - 9 of 9
- RXR ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- MELANOMA DISEASE STRATIFICATION (Inventor)
- CD36 ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- CD36 ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- MELANOMA DISEASE STRATIFICATION (Inventor)
- RXR ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- CD36 ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- MELANOMA DISEASE STRATIFICATION (Inventor)
- RXR ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)