Researcher
Roosmarijn Vandenbroucke
- Keywords (Ghent University):extracellular vesicles, gut inflammation, blood-brain barrier, neuroinflammation, aging, brain targeting
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Cell signalling, Inflammation, Innate immunity, Membrane structure and transport, Gastro-enterology, Infectious diseases, Neurosciences not elsewhere classified, Microbiome
Affiliations
- Board of Governors/Executive Board (Administrative office)
Member
From1 Oct 2022 → Today - Vandenbroucke Lab (Research group)
Responsible
From1 Mar 2018 → Today - Libert Lab (Research group)
Member
From1 Jan 2017 → 28 Feb 2018 - Department of Pharmaceutics (Department)
Member
From1 Jan 2003 → 30 Sep 2008 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2001 → Today
Projects
1 - 10 of 24
- The impact of a SARS-CoV-2 infection on brain pathology and vice versa.From1 Nov 2023 → TodayFunding: FWO fellowships
- The foes and friends among the adaptive immune system in Alzheimer’s diseaseFrom1 Nov 2023 → TodayFunding: BOF - doctoral mandates
- OTULIN in neuroinflammation, multiple sclerosis and Alzheimer pathologyFrom1 Jan 2023 → TodayFunding: BOF - doctoral mandates
- Investigating the biomarker potential and pathological role of extracellular vesicles in Parkinson’s disease.From1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Fine tuning and engaging the immune system to defeat Alzheimer’s disease.From1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Investigating the biomarker potential and pathological role of neuronal- and bacterial- derived extracellular vesicles in Parkinson’s disease.From1 Oct 2021 → 30 Sep 2022Funding: BOF - postdoctoral mandates
- High-precision Sulfur & Selenium isotopic analysis: a novel approach for studying brain redox imbalance & diagnosing/prognosing neurological disorders?From1 Oct 2021 → TodayFunding: BOF - projects
- Extracellular vesicle (EV) transport across the brain barriers: from mechanistic and biological insights towards strategies for delivery of therapeutics to the brain.From1 Jan 2021 → TodayFunding: BOF - projects
- Unraveling the heterogeneity of the choroid plexus tissue and its cell (sub)type-specific response to different inflammatory triggers.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
Publications
11 - 20 of 34
- Special delEVery : extracellular vesicles as promising delivery platform to the brain(2021)
Authors: Marie Pauwels, Charysse Vandendriessche, Roosmarijn Vandenbroucke
- Anti-inflammatory mesenchymal stromal cell-derived extracellular vesicles improve pathology in Niemann-Pick type C disease(2021)
Authors: Lien Van Hoecke, Caroline Van Cauwenberghe, Verena Boerger, Arnout Bruggeman, Jonas Castelein, Griet Van Imschoot, Elien Van Wonterghem, Robin Dittrich, Wouter Claeys, Junhua Xie, et al.
- Involvement of the choroid plexus in the pathogenesis of Niemann-Pick disease type C(2021)
Authors: Lien Van Hoecke, Caroline Van Cauwenberghe, Kristina Dominko, Griet Van Imschoot, Elien Van Wonterghem, Jonas Castelein, Junhua Xie, Wouter Claeys, Charysse Vandendriessche, Anna Kremer, et al.
- Extracellular vesicles : a double-edged sword in sepsis(2021)
Authors: Marlies Burgelman, Charysse Vandendriessche, Roosmarijn Vandenbroucke
- Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer’s disease(2021)
Authors: Charysse Vandendriessche, Sriram Balusu, Caroline Van Cauwenberghe, Marjana Brkic, Marie Pauwels, Nele Plehiers, Arnout Bruggeman, Pieter Dujardin, Griet Van Imschoot, Elien Van Wonterghem, et al.
- Gastric Helicobacter suis infection partially protects against neurotoxicity in A 6-OHDA Parkinson’s disease mouse model(2021)
Authors: Helena Berlamont, Arnout Bruggeman, Eva Bauwens, Charysse Vandendriessche, Elien Clarebout, Junhua Xie, Sofie De Bruyckere, Griet Van Imschoot, Elien Van Wonterghem, Richard Ducatelle, et al.
- Low-grade peripheral inflammation affects brain pathology in the App(NL-G-F)mouse model of Alzheimer's disease(2021)
Authors: Junhua Xie, Nina Gorlé, Charysse Vandendriessche, Griet Van Imschoot, Elien Van Wonterghem, Caroline Van Cauwenberghe, Eef Parthoens, Evelien Van Hamme, Saskia Lippens, Lien Van Hoecke, et al.
- Profiling of extracellular small RNAs highlights a strong bias towards non-vesicular secretion(2021)
Authors: Helena Sork, Mariana Conceicao, Giulia Corso, Joel Nordin, Yi Xin Fiona Lee, Kaarel Krjutskov, Jakub Orzechowski Westholm, Pieter Vader, Marie Pauwels, Roosmarijn Vandenbroucke, et al.
- Helicobacter and the potential role in neurological disorders : there is more than Helicobacter pylori(2021)
Authors: Nina Gorlé, Eva Bauwens, Freddy Haesebrouck, Annemieke Smet, Roosmarijn Vandenbroucke
- Extracellular vesicles in Alzheimer's and Parkinson's disease : small entities with large consequences(2020)
Authors: Charysse Vandendriessche, Arnout Bruggeman, Caroline Van Cauwenberghe, Roosmarijn Vandenbroucke