Researcher
Tim Vervliet
- Disciplines:Cell death, Cell signalling, Molecular and cell biology not elsewhere classified, Cell physiology, Biochemistry and metabolism not elsewhere classified
Affiliations
- Laboratory of Molecular and Cellular Signaling (Division)
Member
From15 Sep 2010 → Today
Projects
1 - 9 of 9
- 'Mito-tracking’ the phenotyping transition of pancreatic stellate cellsFrom1 Oct 2023 → TodayFunding: BOF - projects
- Unraveling the molecular mechanisms underlying Ca2+-signaling modulation by CISD2, a wolfram syndrome-associated gene, and its interplay with Bcl-2 (CaCISD2)From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Regulation of lysosomal function by ryanodine receptormediated Ca2+ release in health and diseaseFrom1 Oct 2020 → TodayFunding: FWO senior postdoctoral fellowship
- Targeting dysregulated IP3 receptor-mediated calcium signaling as an early event in Alzheimer’s disease through its Bcl-2-interaction networkFrom21 Sep 2020 → TodayFunding: FWO fellowships
- IP3R dysregulation as a proximal event in Alzheimer’s disease: exploring and exploiting Bcl-2 proteinsFrom1 Jan 2020 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Molecular mechanisms underlying Ca2+-signaling dysregulation in Wolfram SyndromeFrom1 Oct 2018 → 30 Sep 2020Funding: BOF - Bilateral scientific cooperation
- Elucidating the physiological and patho-physiological role for the interaction of Bcl-2 proteins and the ryanodine receptor.From1 Oct 2016 → 30 Sep 2019Funding: FWO fellowships
- Bcl-2 and ryanodine receptors: physiology, pathophysiology and therapeutics for the heartFrom1 Oct 2016 → 31 Aug 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Novel insights in the interplay between ryanodine receptors and Bcl-2 proteins.From1 Oct 2015 → 30 Sep 2016Funding: BOF - Other initiatives
Publications
11 - 20 of 45
- Cx43 hemichannel microdomain signaling at the intercalated disc enhances cardiac excitability(2021)
Authors: Maarten De Smet, Eef Dries, Matthew Amoni, Tim Vervliet, Geert Bultynck, Karin Sipido
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)(2021)
Authors: Patrizia Agostinis, Geert Bultynck, Abhishek Garg, Manosij Ghosh, Jan Gunst, Muxing Guo, Peter Hoet, Bella Manshian, Jan Parys, Stefaan Soenen, et al.
Pages: 1 - 382 - IP3 Receptor Biology and Endoplasmic Reticulum Calcium Dynamics in Cancer.(2021)
Authors: Jan Parys, Geert Bultynck, Tim Vervliet
Pages: 215 - 237 - EPIC3, a novel Ca2+ indicator located at the cell cortex and in microridges, detects high Ca2+ subdomains during Ca2+ influx and phagocytosis(2020)
Authors: Tim Vervliet, Geert Bultynck, Jan Parys
- MICAL2 is essential for myogenic lineage commitment(2020)
Authors: Nefele Giarratana, Rita La Rovere, Rik Gijsbers, Paolo Carai, Robin Duelen, Tim Vervliet, Geert Bultynck, Domiziana Costamagna, Maurilio Sampaolesi
- Bcl-2-protein family as modulators of IP₃ receptors and other organellar Ca²⁺ channels(2020)
Authors: Hristina Ivanova, Tim Vervliet, Giovanni Monaco, Nicolas Rosa, Jan Parys, Geert Bultynck
- New Insights in the IP3 Receptor and Its Regulation(2020)
Authors: Jan Parys, Tim Vervliet
Pages: 243 - 270 - ABT-199 (Venetoclax), a BH3-mimetic Bcl-2 inhibitor, does not cause Ca2+-signalling dysregulation or toxicity in pancreatic acinar cells(2019)
Authors: Martijn Kerkhofs, Geert Bultynck, Tim Vervliet
Pages: 4402 - 4415 - L-asparaginase-induced apoptosis in ALL cells involves IP3 receptor signaling(2019)
Authors: Tim Vervliet, Jan Parys
- Therapeutic implications of novel peptides targeting ER-mitochondria Ca2+-flux systems(2019)
Authors: Martijn Kerkhofs, Geert Bultynck, Tim Vervliet, Giovanni Monaco
Pages: 1092 - 1103