Development of intrabody-expressing influenza virus vectors to discover new pro- and antiviral host factors Ghent University
Viruses are obligate intracellular parasites that hijack the host cell machinery for their replication. To combat viral diseases, it is crucial to understand how viruses interact with their hosts. For influenza viruses, genome-wide genetic screens have so far primarily revealed host factors that are involved in the early steps of infection, leaving much to learn about host-virus interactions at the late stages of infection. To address this ...