Projects
Development of polyoxometalates as building blocks for supramolecular assemblies of biomolecules KU Leuven
New AlF chelators for fluorine-18 radiolabeling of biomolecules KU Leuven
Positron emission tomography (PET) uses a PET scanner to track radioactive molecules in the body. Fluorine-18 (18F, a radioactive form of fluorine) is a frequently used radionuclide used in PET. The chemical incorporation of 18F into biological molecules (biomolecules) allows visualization of the binding of the biomolecule to its target in the body using a PET scanner. The Al18F method allows to incorporate 18F in various biomolecules in a ...
Biomolecules of the sea for environmental remediation and healthcare Ghent University
The scientific objectives of Biocare marine are to:
Discover and functionalise new antimicrobial agents isolated from the marine environment to help combat the growing threat of broad spectrum antibiotic resistant bacterial infections.
Construct novel wound dressings and tissue regeneration scaffolds using marine biomolecules that hold great promise for the treatment of chronic wounds, and for the ...
BioMolecules Ghent University
IOF-valorisation consortium with central theme the microbial productie and synthesis of bio-based molecules, together with their biotech and chemical engineering tools.
Biomolecules Covalently Anchored on Titanium using Electrophoretic Deposition KU Leuven
With the most prominent causes of orthopedic/dental implant failure being loosening and infection, research is focusing on developing surface coatings that either trigger faster and stronger integration in the host bone (i.e. osseointegration) or that render the surface resistant to contaminating micro-organisms. Within this project, novel implant coatings will be developed that consider both approaches simultaneously. Recently, permanently ...
Rewiring the Streptomyces cell factory for cost-effective production of biomolecules KU Leuven
STREPSYNTH aims to set-up a Streptomyces-based new industrial production platform (SNIP) for high value added biomolecules. Streptomyces lividans was chosen as a bacterial host cell because it has been already shown to be highly efficient for the extracellular production of a number of heterologous molecules that vary chemically, has a robust tradition of industrial fermentation and is fully accessible to genetic intervention. To develop SNIP ...
Modern imaging equipment for the detection and quantification of biomolecules in fundamental and applied research KU Leuven
Development of group(IV) metal oxo clusters as catalysts for the synthesis of biomolecules KU Leuven
The synthesis of biomolecules by non-enzymatic synthetic routes is essential for the development of novel therapeutics; however, current alternatives are onerous to the environment and costly to implement. Therefore, alternatives are highly desired. In this context, this PhD will focus on the development of alternative non-enzymatic synthetic methods for the sustainable and versatile preparation of biomolecules such as peptides, sugars, and ...
Biomolecules in metal-organic frameworks: From optical studies and devices of metal-loaded adeninate MOFs to adsorptive separation of amino acids. KU Leuven
Metal-organic frameworks (MOFs) are a class of hybrid solid materials, built up by coordinative bonds between a wide variety of inorganic metal ion or cluster nodes and organic linking molecules. Their highly ordered three-dimensional architectures are often crystalline and porous, with pore sizes ranging from a few Ångström to ten nanometers. Owing to their large chemical versatility and highly porous architectures, MOFs have been thoroughly ...