This project is aimed at enabling fluorescent labeling of organelles in living cells by quantum dots. At the one hand, silica encapped quantum dots will be targeted to the cytosol by making use of a membrane-disruptive liposomal carrier. At the other hand, a new concept will be tested using thermoresponsive nanoparticles to enable endosomal escape to the cytosol.
Visualization of cell walls components in creal grains using fluorescently labeled enzymes. KU Leuven
Microwave sensing in microfluidics for cell and extracellular vesicle characterization (MESMERIC) KU Leuven
Towards understanding the extractability and functionality of fruit and vegetable derived cell wall polysaccharides using non-conventional extraction techniques KU Leuven
Studying global gene expression changes during hematopoietic development to identify novel regulators of hematopoietic stem cell function KU Leuven
Self-renewal and differentiation are the two primary attributes of all kinds of stem cells. Hematopoietic stem cells (HSCs) are multi-potent stem cells that are responsible for producing all blood cells throughout the lifetime of an organism. Hematopoietic stem cell transplantation (HSCT) is an effective method for treatment of hematopoietic disorders including leukemia and other hematopoietic malignancies, as well as immunodeficiencies. The ...
New strategies for creating cell wall polymer based functional properties in fruits and vegetable based matrices. KU Leuven
The diagnostic and therapeutic potential of the tumor associated antigene xvB5 in non-small cell lung cancer Ghent University
The purpose of the proposal encloses the development of recombinant, humanised anti-xvB5 antibody fragments adapated for radio-immunotherapy and radio-diagnosis in the treatment of non-small cell lung cancer. The biotechnological engineering, the labelling with radio-isotopes and the in vitro and in vivo evaluation in an experimental animal model will be investigated in the research project.