Projects
BLUECC: Commercial exploitation of marine collagen and chitin from marine sources Ghent University
Due to the increased global population, the world will face competition for limited and finite natural resources. On the other hand, the amount of biowaste is increasing and is estimated to be 138 million tons per year in the EU. Also, there are large amounts of underutilized animal species. Both aspects can give us opportunities for developing innovative products. The BlueCC project aims to take underutilized species, by-catch and cleaner ...
A multicenter randomized controlled study comparing connective tissue graft with collagen matrix to re-establish convexity at the buccal aspect of single dental implants Ghent University
Soft tissue augmentation procedures have been recommended to re-establish convexity at the buccal aspect of dental implants. Connective tissue graft is the gold standard but morbidity and patient discomfort have been described. Recently, a collagen matrix has been developed. The primary objective of this RCT is to compare both in terms of increase and stability of buccal soft
tissue profile.
Tissue engineering in Ophthalmology: Regenerating the Anterior Cornea using Self-Aligning Human Recombinant Collagen nanoscaffolds and Corneal Epithelial Stem Cells. University of Antwerp
Tissue engineering in Ophthalmology: Regenerating the Anterior Cornea using Self-Aligning Human Recombinant Collagen nanoscaffolds and Corneal Epithelial Stem Cells. University of Antwerp
Identification of novel genes and pathogenic pathways for osteogenesis imperfecta and Ehlers-Danlos syndrome, paradigm collagen disorders Ghent University
This project aims to identify novel genes and study underlying pathogenetic pathways of osteogenesis imperfecta and Ehlers-Danlos syndrome, two clinically and genetically heterogeneous heritable connective tissue disorders characterized by widespread manifestations of tissue fragility in skin, bone, ligaments, blood vessels and internal organs. Comprehensive study of these conditions is crucial for the understanding of fundamental aspects of ...
The role of dynamic mechanical behavior of altered collagen network under loading to OA statedependent cartilage degradation: combined in vitro and in silico study KU Leuven
Within this PhD project, we will develop and test a multiscale finite element modelling approach to determine cartilage degeneration in the human knee based on in vivo and in vitro experiments. To this end, adaptive multi-scale modeling of the musculoskeletal system is used to relate macroscopic loading to tissue stresses and cell responses, ultimately providing a valuable tool for predicting cartilage degenerative and regenerative responses. ...
Aerosol Jet Printing of Fibrillar Collagens for the Replication of Dense Collagenous Tissues KU Leuven
Bioprinting, or the use of additive manufacturing techniques to produce scaffolds for tissue engineering, has recently been established as a useful tool in tissue engineering and regenerative medicine. However, a major limitation of bioprinting has been the mechanical properties of the printed constructs. While there are many tissues where this may not be treated as a priority, mechanical strength is a particularly important property for any ...