Dissecting the melanoma ecosystem one cell at the time during immunotherapy

This dataset contains count matrices of malignant cells from the scRNA-seq data together with each cell assignment to the malignant state (column name: Malignant_clusters) and count matrices of the entire tumour microenvironment (TME) cells. The full clinical metadata table can be found in the Pozniak et al., (Cell, 2024) paper (Table S1). To explore the malignant data online please use this link to the Shiny app: https://marine-lab.shinyapps.io/Human_melanoma_scRNASeq/ To explore the immune data online please use this link to the Shiny app: https://marine-lab.shinyapps.io/Human_melanoma_immune_scRNASeq/ Moreover, here the images used for Visium Spatial Transciptomic experiment can be found.

Jaar van publicatie:2023

Toegankelijkheid:open

Uitgever:KU Leuven RDR

Licentie:CC-BY-NC-SA-4.0

Formaat:rds, tsv, txt, jpg, tif

Trefwoorden: Immunotherapy, Melanoma, Tumor heterogeneity