Genetic linkage analysis of 15 DFNB loci in a group of Iranian families with autosomal recessive hearing loss Universiteit Antwerpen
Background: Hearing loss (HL) is the most frequent sensory birth defect in humans. Autosomal recessive non-synÂdromic HL (ARNSHL) is the most common type of hereditary HL. It is extremely heterogeneous and over 70 loci (known as DFNB) have been identified. This study was launched to determine the relative contribution of more frequent loci in a cohort of ARNSHL families. Methods: Thirty-seven Iranian families including 36 ARNSHL families and 1 ...