Epigenetics in toxicology: the implications of epigenetic alterations driven by external exposures for human health Vrije Universiteit Brussel
The prospect that non-genotoxic environmental exposures of physical, chemical or social nature act on epigenetic mechanisms opens a new emerging field in toxicology. Epigenetics refers to the stable changes in gene expression programming that could alter the phenotype in absence of a change in DNA sequence. Epigenetic modifications, which include amongst others DNA methylation, covalent modifications of histone tails, and regulation by ...