Publicaties
Recent developments in genetics and medically assisted reproduction Vrije Universiteit Brussel KU Leuven Universiteit Gent
Two leading European professional societies, the European Society of Human Genetics and the European Society for Human Reproduction and Embryology, have worked together since 2004 to evaluate the impact of fast research advances at the interface of assisted reproduction and genetics, including their application into clinical practice. In September 2016, the expert panel met for the third time. The topics discussed highlighted important issues ...
Self-operated endovaginal telemonitoring versus traditional monitoring of ovarian stimulation in assisted reproduction Vrije Universiteit Brussel Universiteit Gent
STUDY QUESTION: Does self-operated endovaginal telemonitoring (SOET) of the ovarian stimulation phase in IVF/ICSI produce similar laboratory, clinical, patient reported and health-economic results as traditional monitoring (non-SOET)?
SUMMARY ANSWER: SOET is not inferior to traditional monitoring (non-SOET).
WHAT IS KNOWN ALREADY: Monitoring the follicular phase is needed to adapt gonadotrophin dose, detect threatening ...
Towards complication-free assisted reproduction technology Vrije Universiteit Brussel
Assisted reproductive technology (ART) has vastly improved over the last 40 years, from a frequently unsuccessful and complicated procedure requiring hospital admission and routine laparoscopy to a fairly simple outpatient technique with relatively high success rates. However, it is important to stress that ART is not without risk and medical complications may still occur. The incidence of most of these ART-related complications is associated ...
Current issues in medically assisted reproduction and genetics in Europe Vrije Universiteit Brussel KU Leuven
STUDY QUESTION: How has the interface between genetics and assisted reproduction technology (ART) evolved since 2005?
SUMMARY ANSWER: The interface between ART and genetics has become more entwined as we increase our understanding about the genetics of infertility and we are able to perform more comprehensive genetic testing.
WHAT IS KNOWN ALREADY: In March 2005, a group of experts from the European Society of Human Genetics ...
AI language models in human reproduction research Vrije Universiteit Brussel
Artificial intelligence (AI)-driven language models have the potential to serve as an educational tool, facilitate clinical decision-making, and support research and academic writing. The benefits of their use are yet to be evaluated and concerns have been raised regarding the accuracy, transparency, and ethical implications of using this AI technology in academic publishing. At the moment, Chat Generative Pre-trained Transformer (ChatGPT) is ...
Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight Vrije Universiteit Brussel
Children conceived through assisted reproductive technologies (ART) have an elevated risk of lower birthweight, yet the underlying cause remains unclear. Our study explores mitochondrial DNA (mtDNA) variants as contributors to birthweight differences by impacting mitochondrial function during prenatal development. We deep-sequenced the mtDNA of 451 ART and spontaneously conceived (SC) individuals, 157 mother-child pairs and 113 individual ...