Researcher
Hendrik Jan Thibaut
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 2006 → Today
Projects
1 - 1 of 1
- Uncovering kinase inhibitor resistance mechanisms via CRISPR-based gain-of-function mutagenesis.From12 Jul 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
21 - 30 of 64
- The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways(2021)
Authors: Manon Laporte, Hendrik Jan Thibaut, Katleen Martens, Piet Maes, Lieve Naesens, Annelies Stevaert
- Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2(2021)
Authors: Jim Baggen, Els Vanstreels, Sander Jansen, Bram Boeckx, Vincent Geudens, Dirk Jochmans, Joost Wauters, Els Wauters, Bart Vanaudenaerde, Diether Lambrechts, et al.
Pages: 435 - + - enAsCas12a Enables CRISPR-Directed Evolution to Screen for Functional Drug Resistance Mutations in Sequences Inaccessible to SpCas9(2021)
Authors: Maarten Jacquemyn, Tim Dierckx, Hendrik Jan Thibaut, Dirk Daelemans
Pages: 208 - 224 - Comparing immunogenicity and protective efficacy of the yellow fever 17D vaccine in mice(2021)
Authors: Ji Ma, Robbert Boudewijns, Thomas Vercruysse, Hendrik Jan Thibaut, Johan Neyts, Kai Dallmeier
Pages: 2279 - 2290 - A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate(2020)
Authors: Lorena Sanchez Felipe, Thomas Vercruysse, Sapna Sharma, Ji Ma, Viktor Lemmens, Robbert Boudewijns, Bert Malengier-Devlies, Laurens Liesenborghs, Suzanne Kaptein, Madina Rasulova, et al.
Pages: 320 - 325 - STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters(2020)
Authors: Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne Kaptein, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, et al.
Pages: 5838 - 5838 - Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity(2020)
Authors: Suzanne Kaptein, Sofie Jacobs, Lana Langendries, Laura Seldeslachts, Sebastiaan ter Horst, Laurens Liesenborghs, Bart Hens, Valentijn Vergote, Elisabeth Heylen, Rana Abdelnabi, et al.
Pages: 26955 - 26965 - Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence(2019)
Authors: Jim Baggen, Pieter Leyssen, Erik Verbeken, Johan Neyts, Hendrik Jan Thibaut
Pages: 1076 - 1085 - Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus(2019)
Authors: Jim Baggen, Hendrik Jan Thibaut
- Viral engagement with host (co-)receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid(2019)
Authors: Hendrik Jan Thibaut, Kristina Lanko, Kai Dallmeier, Leen Delang, Pieter Leyssen, Johan Neyts
Patents
1 - 10 of 10
- Coronavirus vaccines (Inventor)
- Novel compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient (Inventor)
- 1,3-di-oxo-indene derivative, pharmaceutically acceptable salt or optical isomer thereof, preparation method thereof, and pharmaceutical composition containing same as an antiviral, active ingredient (Inventor)
- Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases (Inventor)
- Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases (Inventor)
- Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient (Inventor)
- Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient (Inventor)
- 1,3-di-oxo-indene derivative, pharmaceutically acceptable salt or optical isomer thereof, preparation method thereof, and pharmaceutical composition containing same as an antiviral, active ingredient (Inventor)
- 1,3-di-oxo-indene derivative, pharmaceutically acceptable salt or optical isomer thereof, preparation method thereof, and pharmaceutical composition containing same as an antiviral, active ingredient (Inventor)
- Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases (Inventor)