Researcher
Johan Swinnen
- Disciplines:Oncology, Medical systems biology
Affiliations
- Laboratory of Lipid Metabolism and Cancer (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Lipid Metabolism and Cancer (Division)
Member
From1 Jan 2012 → Today - Clinical and Experimental Endocrinology (Division)
Member
From1 Jan 2003 → 31 Dec 2011 - Department of Development and Regeneration (Department)
Member
From1 Oct 2000 → 31 Dec 2002
Infrastructure
1 - 2 of 2
- An high-throughput automated small molecule screening platform (Consortium coordinator)
- Next Generation Magnetic Resonance Mass Spectrometry. (Consortium coordinator)
Projects
1 - 10 of 47
- Preclinical targeting of monoacylglycerol lipase (MGLL) to prevent metastasis and immune evasion in pancreatic cancerFrom1 Oct 2022 → TodayFunding: Foundations, funds and other with scientific goal
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- Multimodal Coherent Raman Scattering /Fluorescence Lifetime Imaging Microscopy systemFrom2 Aug 2022 → TodayFunding: Other federal scientific institutions
- Een geautomatiseerd hoge capaciteit analytisch platform voor lipiden en metabolietenFrom1 May 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Aggressive salivary gland neoplasms: institutional-international collaborative evaluation of advances in clinical management and translational research into tumor biologyFrom11 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Exploiting acquired vulnerabilities in fatty acid metabolism to overcome therapy resistance in castration resistant prostate cancerFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- The role of Rer1 in ER-related homeostatic mechanismsFrom1 Jan 2021 → 31 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Exploitation of lipid metabolism in improving cancer immune checkpoint therapy responseFrom1 Jan 2021 → TodayFunding: FWO research project
- Lipometrix – towards an integrated lipidomics platform.From1 Nov 2020 → TodayFunding: BOF - research organisations
Publications
1 - 10 of 114
- NOVEL THERAPY FOR BRAIN METASTASIS(2022)
Authors: Shuncong Wang, Yicheng Ni, Guy Bormans, Johannes Swinnen
- The ApoA-I mimetic peptide 5A enhances remyelination by promoting clearance and degradation of myelin debris(2022)
Authors: Jonas Dehairs, Johannes Swinnen
- Perilipin-2 limits remyelination by preventing lipid droplet degradation(2022)
Authors: Jonas Dehairs, Hannelore Kemps, Johannes Swinnen
- Monounsaturated Fatty Acids: Key Regulators of Cell Viability and Intracellular Signaling in Cancer(2022)
Authors: Johannes Swinnen
Pages: 1354 - 1364 - Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers(2022)
Authors: Ali Talebi, Wout De Wispelaere, Regina Esi Mensimah Baiden-Amissah, Guy Eelen, Emanuele Berardi, Johannes Swinnen, Peter Carmeliet, Diether Lambrechts, Sarah-Maria Fendt, Daniela Annibali, et al.
- FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer's disease expressing APOE4(2022)
Authors: Etienne Waelkens, Rita Derua, Johannes Swinnen, Jonas Dehairs
- PMP22 OVEREXPRESSION CAUSES LIPID RECYCLING DEFECTS THAT ALTERS THE PLASMA MEMBRANE IN CMT1A(2022)
Authors: Robert Ciarán Prior, Vincent de Laat, Jonas Dehairs, Philip Van Damme, Johannes Swinnen, Ludo Van Den Bosch
Pages: S108 - S108 - Inter-organellar Communication in Parkinson's and Alzheimer's Disease: Looking Beyond Endoplasmic Reticulum-Mitochondria Contact Sites(2022)
Authors: Stephanie Vrijsen, Mara Del Vecchio, Johannes Swinnen, Patrizia Agostinis, Joris Winderickx, Peter Vangheluwe, Willem Annaert
- Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis(2022)
Authors: Diede Houbaert, Maria Livia Sassano, Mila Borri, Jelle Verhoeven, Madhur Agrawal, Gabriele Bergers, Maria Dewerchin, Johannes Swinnen, Peter Carmeliet, Patrizia Agostinis
- Regulated IRE1 alpha-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer(2022)
Authors: Johannes Swinnen
Patents
1 - 5 of 5
- Screening methods for compounds modulating polyamine transport (Inventor)
- Combination treatment of arsenic oxide and antiandrogens (Inventor)
- Cancer phospholipidome (Inventor)
- CANCER PHOSPHOLIPIDOME (Inventor)
- PHOSPHOLIPID PROFILING OF CANCER (Inventor)