Multi-drug resistance in malaria in combination therapy : assessment of specific markers and development of innovative, rapid and simple diagnostics
To assess specific genetic markers for Artemisinin-based combination drugs resistance and the development of innovative, rapid and simple diagnostics.
To develop and evaluate in disease endemic countries accurate low-tech molecular diagnostic tests for malaria, and evaluate their utility for detecting treatment failure in antimalarial therapy trials.To identify alleles of candidate resistance ...
MELLODDY will demonstrate how the pharmaceutical industry can better leverage its data assets to virtualize the Drug Discovery (DD) process with world-leading Machine Learning (ML) technologies as an answer to the ever-increasing challenges and stricter regulatory requirements it is facing. The lack of a tested, secure and privacy-preserving platform for federated machine learning that enables pharmaceutical partners to extract DD-relevant ...
New mechanisms of drug resistance in malaria parasites: a molecular, epidemiological and social study
Neuro-TARGET : integrated platform for target identification, validation and drug discovery with applications for neurodegenerative diseases. Vrije Universiteit Brussel
Pump Prime Funding for EUROCOVID (IMI2) European Cooperation for anti-Viral Drug discovery and preperadnness for current and emerging coronavirus outbreaks
more than 600K man and women worldwide, imposing an unprecedented lockdown on world-wide scale, with huge socioeconomic
consequences. Health-care professionals are currently in the frontline of this “war”, saving lives, protecting the
medically fragile population, while governments are trying to contain the spreading ...
Establishment of an integrated and synergistic network to address the challenge of multiple drug resistant TBC (MDR-TB) facing the EU. The objective will be attained through the establishment of a European consortium of expert partners with extensive experience in the conduct of basic and clinical research relating to MDR-TB, TB control and epidemiology. This Consortium will achieve this by:Conducting an extensive and focused programme of ...
To develop a standardised bioluminiscent in vitro model for blood stream trypanosomes for the screening of marine components.
- Development of in vitro system for T. congolense.
- Development of bioluminiscent T. congolense strains.
- Limited in vitro drug screening of marine components and existing trypanocides in order to proof that the in vitro model can ...
Development of a two-approach plate system for the fast and simultaneous detection of MDR and XDR M. tuberculosis
Tuberculosis (TB) continues being a leading cause of death due to a single infectious disease agent. The HIV/AIDS pandemic and the emergence of drug resistance are compounding factors that hinder the control of the disease. Associated with this problem is the emergence of multidrug-resistant (MDR) strains of Mycobacterium tuberculosis, defined as strains resistant to at least isoniazid and rifampicin, the most valuable drugs in the treatment ...