Researcher
Dietmar Thal
- Disciplines:Anatomical pathology, Neurological and neuromuscular diseases
Affiliations
- Laboratory for Neuropathology (Lab)
Responsible
From1 May 2019 → Today - Translational Cell & Tissue Research (Division)
Member
From1 May 2019 → Today - Laboratory for Neuropathology (Lab)
Member
From1 Apr 2016 → 30 Apr 2019 - Department of Neurosciences (Department)
Member
From1 Oct 2015 → 31 Mar 2016
Projects
1 - 10 of 23
- Necroptosis and pyroptosis pathway inhibition in mouse models of Alzheimer's disease pathology: Can we protect neurons from dying?From1 Jan 2024 → TodayFunding: Private funding of national origin - undefined
- Cell death and neuron degeneration in Amyotrophic Lateral Sclerosis (ALS)From3 Nov 2022 → 15 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis (ALS): cell death pathways and/or aberrant communication between cell body and neuromuscular junctionsFrom1 Oct 2022 → TodayFunding: BOF - projects
- Selective vulnerability in Alzheimer’s disease and frontotemporal degeneration: integration of postmortem MRI, mass-spectrometry and histopathologyFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Risk factors for Alzheimer’s diseaseFrom21 Jun 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Aβ and tau pathology in the retina of Alzheimer’s disease patients and non-demented elderly individuals and its relation to the brain pathologyFrom1 Mar 2021 → TodayFunding: BOF - doctoral mandates
- Investigating the role of tau aggregates in neurodegenerationFrom15 Feb 2021 → TodayFunding: FWO fellowships
- Risk factors for neuropathological hallmark lesions and cell death in preclinical and symptomatic Alzheimer’s disease: a chance for age-of-onset prediction?From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Deciphering Tau structure and oligomerization propensities: Towards innovative therapeutics, prognostics and diagnosticsFrom1 Jan 2021 → 31 Dec 2023Funding: IOF - technology validation in lab
Publications
1 - 10 of 128
- Regulated cell death and its role in Alzheimer's disease and amyotrophic lateral sclerosis.(2024)
Authors: Dietmar Thal
Pages: 69 - Correction: Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution.(2024)
Authors: Dietmar Thal
Pages: 28 - TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish(2024)
Authors: Philip Van Damme, Dietmar Thal, Valérie Bercier, Ludo Van Den Bosch
- Local structural preferences in shaping tau amyloid polymorphism(2024)
Authors: Grigoria Tsaka, Rodrigo Gallardo, Dietmar Thal, Frederic Rousseau, Joost Schymkowitz
- Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution(2024)
Authors: Francisco Pestana, Catherine Marneffe, Dietmar Thal
- Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions(2024)
Authors: Lies De Groef, Dietmar Thal
Pages: 728 - 740 - Primary retinal tauopathy: A tauopathy with a distinct molecular pattern(2024)
Authors: Grzegorz Walkiewicz, Sophie Lemmens, Lies De Groef, Dietmar Thal
Pages: 330 - 340 - TDP‑43 pathology is associated with increased tau burdens and seeding(2023)
Authors: Sandra Oliveira Tomé, Grigoria Tsaka, Klara Gawor, Philip Van Damme, Ludo Van Den Bosch, Rik Vandenberghe, Frederic Rousseau, Joost Schymkowitz, Dietmar Thal
- A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons(2023)
Authors: Jimmy Beckers, Dietmar Thal, Ludo Van Den Bosch, Philip Van Damme
- MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease(2023)
Authors: Sriram Balusu, Nicky Thrupp, Dries T'Syen, Annerieke Sierksma, Dietmar Thal, Mark Fiers, Bart De Strooper
Pages: 1176 - +