Researcher
Kris Vleminckx
- Keywords:cancer research, rare diseases, CRISPR/Cas9, Developmental biology
- Disciplines:Cell signalling, Developmental genetics, Genome structure and regulation, Developmental biology, Vertebrate biology, Epigenetics, Genetics, Animal developmental and reproductive biology, Cancer biology
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Jan 2013 → 30 Sep 2018 - Department of Biomedical molecular biology (Department)
Member
From1 Jan 1999 → Today
Projects
1 - 10 of 30
- Morphological, molecular and functional insights into the cardiovascular complications of autosomal dominant polycystic kidney diseaseFrom1 Nov 2023 → TodayFunding: BOF - postdoctoral mandates
- Interspecies exploration of the (post)transcriptional and epigenomic signatures associated with Wilms' tumor formationFrom1 Nov 2023 → TodayFunding: FWO fellowships
- CRISPR-mediated mapping of genetic dependencies in well-differentiated and dedifferenciated liposarcomaFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Pathomechanistic study of RCBTB1-associated inherited retinal disease using Xenopus tropicalis and patient-derived induced pluripotent stem cellsFrom1 Oct 2022 → 31 Oct 2023Funding: BOF - doctoral mandates
- Functional assessment of cis-regulatory elements of inherited retinal diseases (IRDs) in Xenopus tropicalisFrom1 May 2022 → 30 Apr 2023Funding: BOF - doctoral mandates
- Investigating the role and mechanism of EZH2 in immune checkpoint resistance in tumors with Wnt/ß-catenin pathway activationFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Identification et caractérisation des facteurs de dépendance dans un modèle génétique de tumeur desmoïde de Xenopus tropicalisFrom1 Sep 2020 → 31 Aug 2022Funding: Other international institutions, not mentioned elsewhere
- Precision medicine in inherited blindness using integrated omics in human and animal modelsFrom1 Jan 2020 → TodayFunding: BOF - projects
- Identifying and characterizing dependency factors in a genetic Xenopus tropicalis desmoid tumor modelFrom15 Jul 2019 → 14 Jul 2021Funding: Foreign foundations, funds with scientific view
- CRISPR/Cas9-based in vivo identification of EZH2 as a therapeutic target in desmoid tumors and small cell lung cancerFrom1 Jan 2019 → 31 Dec 2019Funding: Foundations, funds and other with scientific goal
Publications
31 - 40 of 62
- Chemical inhibition of a subset of Arabidopsis thaliana GSK3-like kinases activates brassinosteroid signaling(2009)
Authors: Bert De Rybel, Dominique Audenaert, Grégory Vert, Wilfried Rozhon, Juliane Mayerhofer, Silvie Coutuer, Tinneke Denayer, Leentje Jansen, Long Nguyen, Isabelle Vanhoutte, et al.
Pages: 594 - 604 - Inhibition of the canonical Wnt signaling pathway during craniofacial development: impact on the craniofacial phenotype of Xenopus tadpoles(2009)Volume: 49
Authors: Emilie Descamps, Kris Vleminckx, Dominique Adriaens
Pages: E221 - E221 - Canonical Wnt signaling controls proliferation of retinal stem/progenitor cells in postembryonic Xenopus eyes(2008)
Authors: Tinneke Denayer, M LOCKER, C BORDAY, Tom Deroo, Sylvie Janssens, A HECHT, Frans Van Roy, M PERRON, Kris Vleminckx
Pages: 2063 - 2074 - Hearing loss in Waardenburg syndrome: a systematic review
Authors: J Song, Y Feng, Frederic Acke, Paul Coucke, Kris Vleminckx
Pages: 416 - 425 - Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues
Authors: William A Munoz, Malgorzata Kloc, Kyucheol Cho, Moonsup Lee, Ilse Hofmann, Amy Sater, Kris Vleminckx, Pierre D McCrea
- An atlas of Wnt activity during embryogenesis in Xenopus tropicalis
Authors: Caroline Borday, Karine Parain, Hong Tran Thi, Kris Vleminckx, Muriel Perron, Anne H Monsoro-Burq
- Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation
Authors: Caroline Borday, Pauline Cabochette, Karine Parain, Nicolas Mazurier, Sylvie Janssens, Hong Tran Thi, Belaïd Sekkali, Odile Bronchain, Kris Vleminckx, Morgane Locker, et al.
Pages: 3499 - 3509 - The role of Wnt in cell signaling and cell adhesion during early vertebrate development
Authors: Sylvie Janssens, Ellen Crabbe, Kris Vleminckx
Pages: 2352 - 2366 - Cell migration during development
Authors: Ellen Crabbe, Kris Vleminckx
Number of pages: 1 - Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos
Authors: Thomas Naert, Dieter Tulkens, Nicole A. Edwards, Nikko-Ideen Shaidani, Marcin Wlizla, Suzan Demuynck, Marko E. Horb, Aaron M. Zorn, Kris Vleminckx